No correlative evidence of costs of infection or immunity on leucocyte telomere length in a wild population of Soay sheep DOI Creative Commons
Sanjana Ravindran,

Sarah Underwood,

Jennifer Dorrens

et al.

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 291(2020)

Published: April 2, 2024

Telomere length (TL) is a biomarker hypothesized to capture evolutionarily and ecologically important physiological costs of reproduction, infection immunity. Few studies have estimated the relationships among status, immunity, TL fitness in natural systems. The hypothesis that short telomeres predict reduced survival because they reflect costly consequences immune investment remains largely untested. Using longitudinal data from free-living Soay sheep population, we tested whether leucocyte was predicted by with nematode parasites antibody levels against those parasites. Helminth parasite burdens were positively associated both lambs adults, which not consistent reflecting costs. We found no association between helminth-specific IgG either young or old individuals suggests does an activated response immunosenescence. Furthermore, support for acting as mediator trade-offs infection, immunity subsequent wild. Our results suggest while variation could short-term resource environmental conditions, it nor behave like marker individual's response.

Language: Английский

No correlative evidence of costs of infection or immunity on leucocyte telomere length in a wild population of Soay sheep DOI Creative Commons
Sanjana Ravindran,

Sarah Underwood,

Jennifer Dorrens

et al.

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 291(2020)

Published: April 2, 2024

Telomere length (TL) is a biomarker hypothesized to capture evolutionarily and ecologically important physiological costs of reproduction, infection immunity. Few studies have estimated the relationships among status, immunity, TL fitness in natural systems. The hypothesis that short telomeres predict reduced survival because they reflect costly consequences immune investment remains largely untested. Using longitudinal data from free-living Soay sheep population, we tested whether leucocyte was predicted by with nematode parasites antibody levels against those parasites. Helminth parasite burdens were positively associated both lambs adults, which not consistent reflecting costs. We found no association between helminth-specific IgG either young or old individuals suggests does an activated response immunosenescence. Furthermore, support for acting as mediator trade-offs infection, immunity subsequent wild. Our results suggest while variation could short-term resource environmental conditions, it nor behave like marker individual's response.

Language: Английский

Citations

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