Introduction to the special issue: challenges and opportunities in the fight against neglected tropical diseases: a decade from the London Declaration on NTDs

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2023, Volume and Issue: 378(1887)

Published: Aug. 20, 2023

Twenty neglected tropical diseases (NTDs) are currently prioritised by the World Health Organization for eradication, elimination as a public health problem, of transmission or control 2030. This issue celebrates progress made since 2012 London Declaration on NTDs and discusses challenges faced to achieve these goals. It comprises 14 contributions spanning tackled intensified disease management those addressed preventive chemotherapy. Although COVID-19 negatively affected NTD programmes, it also served spur new multisectoral approaches strengthen school-based systems. The highlights needs improve impact survey design, evaluate diagnostics, understand consequences heterogeneous prevalence human movement, potential alternative treatment strategies importance zoonotic transmission. article is part theme 'Challenges opportunities in fight against diseases: decade from NTDs'.

Language: Английский

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Jordan eliminates leprosy disease and moves to post-elimination surveillance

Nature Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: March 10, 2025

Language: Английский

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Epidemiological, clinical, and geographical characterization of Leprosy in the County of Santarém-Pará: Insights for effective control and targeted intervention

PLoS neglected tropical diseases, Journal Year: 2024, Volume and Issue: 18(3), P. e0012063 - e0012063

Published: March 20, 2024

Leprosy is an infectious disease characterized by slow and chronic evolution, caused Mycobacterium leprae or lepromatosis , intracellular alcohol-acid-resistant (BAAR) bacillus. The objective of this study was to provide epidemiological, clinical, geographic characterization leprosy in the city Santarém-Pará during period 2011–2020. A cross-sectional, descriptive, quantitative approach used, employing maps tables illustrate clinical epidemiological variables, including: sex, age, race, area residence, operational classification, form, number skin lesions, affected nerves, health units. During analyzed period, 581 cases were diagnosed, resulting following cumulative incidence rates: male (60%); age over 15 years (94%); urban (73%); multibacillary (74%); borderline form (46%); lesions greater than 5 (34%); no nerves (68%). In perimeter, a higher observed central with 133 cases. However, unit reporting largest belonged southern area, specifically Basic Health Unit Nova República, 48 This highlights need characterize nuances its variability within environment, according different areas. Further research essential inform implementation public policies aimed at addressing population highest vulnerability index, thereby reducing rates Santarém.

Language: Английский

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Geospatial Analysis of Child Leprosy Cases and Block-Level Endemicity in Raigad District, Maharashtra (2018-19 to 2023-24)

Indian Journal of Child Health, Journal Year: 2024, Volume and Issue: 11(10), P. 93 - 99

Published: Dec. 21, 2024

Background: Leprosy remains a public health Problem in few pockets of India, including the Raigad district, where prevalence rate exceeds 1/10000 population and child proportion is notably high. Understanding its spatial distribution crucial guide for targeted interventions as it reflects community's ongoing case transmission especially endemic areas due to possibility close contact high exposure levels community. Aims: The study aimed analyse geographical patterns leprosy Maharashtra identify high-risk areas. Methods: A retrospective data analysis 3,927 cases, 572 children aged ≤14 years was conducted using open-source GIS software (Version 3.8) from April 2018 March 2024. Results: Children constituted 12% with 3.3 per 100,000 population. identified Karjat Panvel hotspots over 100 new cases annually. Other blocks exhibited varying endemicity uneven Child cases. Kernel density estimation revealed high-density PB MB multiple habitats. Conclusion: highlights heterogeneity leprosy, emphasizing that mapping can be essential tools devising strategies reduce incidence leprosy.

Language: Английский

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