Neurofeedback: new territories and neurocognitive mechanisms of endogenous neuromodulation DOI Creative Commons
James Sulzer, T. Dorina Papageorgiou, Rainer Goebel

et al.

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 379(1915)

Published: Oct. 21, 2024

Neurofeedback (NF) is endogenous neuromodulation of circumscribed brain circuitry. While its use real-time activity in a closed-loop system similar to brain–computer interfaces, instead controlling an external device like the latter, goal NF change targeted function. In this special issue on NF, we present current and future methods for extracting manipulating neural function, how these may reveal new insights about applications, rarely discussed ethical considerations guiding interpreting others. Together, articles outline possibilities impact real world, poising influence development more effective personalized protocols, improving understanding underlying psychological neurological mechanisms enhancing treatment precision various psychiatric conditions. This article part theme ‘Neurofeedback: territories neurocognitive neuromodulation’.

Language: Английский

Advances and challenges in neuroimaging-based pain biomarkers DOI Creative Commons
Libo Zhang, Yuxin Chen, Zhenjiang Li

et al.

Cell Reports Medicine, Journal Year: 2024, Volume and Issue: 5(10), P. 101784 - 101784

Published: Oct. 1, 2024

SummaryIdentifying neural biomarkers of pain has long been a central theme in neuroscience. Here, we review the state-of-the-art candidates for acute and chronic pain. We classify these potential into five categories based on nature their target variables, including (1) within-individual perception, (2) between-individual sensitivity, (3) discriminability pain, as well (4) assessment (5) prospective For each category, provide synthesized candidate developed using neuroimaging techniques functional magnetic resonance imaging (fMRI), structural (sMRI), electroencephalography (EEG). also discuss conceptual practical challenges developing Addressing challenges, optimal can be to deepen our understanding how brain represents ultimately help alleviate patients' suffering improve well-being.Graphical abstract

Language: Английский

Citations

9
Modulating subjective pain perception with decoded Montreal Neurological Institute-space neurofeedback: a proof-of-concept study DOI Creative Commons
Taryn Berman, Cody A. Cushing,

S Manuel

et al.

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 379(1915)

Published: Oct. 21, 2024

Pain is a complex emotional experience that still remains challenging to manage. Previous functional magnetic resonance imaging (fMRI) studies have associated pain with distributed patterns of brain activity (i.e. decoders), but it unclear whether these observations reflect causal mechanisms. To address this question, we devised new neurofeedback approach using real-time decoding fMRI data test if modulating pain-related multivoxel could lead changes in subjective experience. We first showed ratings can indeed be accurately predicted based on the stimulus intensity independent signature (SIIPS) and neurologic (NPS). Next, trained participants ( n = 16) double-blinded decoded experiment up- or downregulate SIIPS. Our results indicate learn expression SIIPS independently from NPS expression. Importantly, success training was perceived painful stimulation following intervention. Taken together, closed-loop efficiently conducted priori decoders pain, potentially opening up range applications for neurofeedback, both clinical basic science purposes. This article part theme issue ‘Neurofeedback: territories neurocognitive mechanisms endogenous neuromodulation’.

Language: Английский

Citations

4
Psilocybin-assisted neurofeedback for the improvement of executive functions: a randomized semi-naturalistic-lab feasibility study DOI Creative Commons
Stefanie Enriquez‐Geppert,

Jaroslav Krc,

Fiachra O'Higgins

et al.

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 379(1915)

Published: Oct. 21, 2024

Executive function deficits, common in psychiatric disorders, hinder daily activities and may be linked to diminished neural plasticity, affecting treatment training responsiveness. In this pioneering study, we evaluated the feasibility preliminary efficacy of psilocybin-assisted frontal-midline theta neurofeedback (NF), a neuromodulation technique leveraging neuroplasticity, improve executive functions (EFs). Thirty-seven eligible participants were randomized into an experimental group (

Language: Английский

Citations

2
Neurofeedback: new territories and neurocognitive mechanisms of endogenous neuromodulation DOI Creative Commons
James Sulzer, T. Dorina Papageorgiou, Rainer Goebel

et al.

Philosophical Transactions of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 379(1915)

Published: Oct. 21, 2024

Neurofeedback (NF) is endogenous neuromodulation of circumscribed brain circuitry. While its use real-time activity in a closed-loop system similar to brain–computer interfaces, instead controlling an external device like the latter, goal NF change targeted function. In this special issue on NF, we present current and future methods for extracting manipulating neural function, how these may reveal new insights about applications, rarely discussed ethical considerations guiding interpreting others. Together, articles outline possibilities impact real world, poising influence development more effective personalized protocols, improving understanding underlying psychological neurological mechanisms enhancing treatment precision various psychiatric conditions. This article part theme ‘Neurofeedback: territories neurocognitive neuromodulation’.

Language: Английский

Citations

2