VITAP: A High Precision Tool for DNA and RNA Viral Classification Based On Meta-omic Data DOI Creative Commons
Min Wang,

Kaiyang Zheng,

Jianhua Sun

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: May 30, 2024

Abstract The rapid growth in the number of newly identified DNA and RNA viral sequences underscores urgent need for an accurate comprehensive classification system all realms at different levels. Here, a new Viral Taxonomic Assignment Pipeline (VITAP) is established, which addresses these challenges by integrating alignment-based techniques with graph, offering high precision classifying both providing confidence scores each taxonomic unit. This tool automatically updates its database sync latest references from International Committee on Taxonomy Viruses (ICTV), efficiently as short 1000 base pairs to genus level. VITAP's performance surpasses existing methods accuracy, recall across phyla. Its application deep-sea viromes has led significant updates, more diversity information viruses deep-sea. VITAP available https://github.com/DrKaiyangZheng/VITAP.

Language: Английский

VITAP: a high precision tool for DNA and RNA viral classification based on meta-omic data DOI Creative Commons

Kaiyang Zheng,

Jianhua Sun,

Yantao Liang

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: March 5, 2025

The rapid growth in the number of newly identified DNA and RNA viral sequences underscores need for an accurate comprehensive classification system all realms at different taxonomic levels. Here, we establish Viral Taxonomic Assignment Pipeline (VITAP), which addresses challenges by integrating alignment-based techniques with graphs, offering high precision classifying both providing confidence level each unit. This tool automatically updates its database sync latest references from International Committee on Taxonomy Viruses (ICTV), efficiently as short 1,000 base pairs to genus level. VITAP possesses good generalization capabilities, maintaining accuracy comparable other pipelines while achieving higher annotation rates across most phyla. Its application deep-sea viromes has led significant updates, diversity information viruses deep-sea. is available https://github.com/DrKaiyangZheng/VITAP . High-throughput sequencing retrieves diverse environments, but these can be difficult classify. here developed a assignment pipeline that classifies incomplete (as 1000-bp) down

Language: Английский

Citations

1
VITAP: A High Precision Tool for DNA and RNA Viral Classification Based On Meta-omic Data DOI Creative Commons
Min Wang,

Kaiyang Zheng,

Jianhua Sun

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: May 30, 2024

Abstract The rapid growth in the number of newly identified DNA and RNA viral sequences underscores urgent need for an accurate comprehensive classification system all realms at different levels. Here, a new Viral Taxonomic Assignment Pipeline (VITAP) is established, which addresses these challenges by integrating alignment-based techniques with graph, offering high precision classifying both providing confidence scores each taxonomic unit. This tool automatically updates its database sync latest references from International Committee on Taxonomy Viruses (ICTV), efficiently as short 1000 base pairs to genus level. VITAP's performance surpasses existing methods accuracy, recall across phyla. Its application deep-sea viromes has led significant updates, more diversity information viruses deep-sea. VITAP available https://github.com/DrKaiyangZheng/VITAP.

Language: Английский

Citations

1