Genes for cooperation are not more likely to be carried by plasmids DOI Creative Commons
Anna E. Dewar, Laurence J. Belcher, Thomas W. Scott

et al.

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 291(2017)

Published: Feb. 28, 2024

Cooperation is prevalent across bacteria, but risks being exploited by non-cooperative cheats. Horizontal gene transfer, particularly via plasmids, has been suggested as a mechanism to stabilize cooperation. A key prediction of this hypothesis that genes which are more likely be transferred, such those on should code for cooperative traits. Testing requires identifying all cooperation in bacterial genomes. However, previous studies used method misses some these To solve this, we new genomics tool, SOCfinder, uses three distinct modules identify kinds We compared where were located 4648 genomes from 146 species. In contrast the hypothesis, found no evidence plasmid Instead, opposite—that carried chromosomes. Overall, vast majority not suggesting general kin selection sufficient explain prevalence bacteria.

Language: Английский

A phylogenetic approach to comparative genomics DOI
Anna E. Dewar, Laurence J. Belcher, Stuart A. West

et al.

Nature Reviews Genetics, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 8, 2025

Language: Английский

Citations

1
Genes for cooperation are not more likely to be carried by plasmids DOI Creative Commons
Anna E. Dewar, Laurence J. Belcher, Thomas W. Scott

et al.

Proceedings of the Royal Society B Biological Sciences, Journal Year: 2024, Volume and Issue: 291(2017)

Published: Feb. 28, 2024

Cooperation is prevalent across bacteria, but risks being exploited by non-cooperative cheats. Horizontal gene transfer, particularly via plasmids, has been suggested as a mechanism to stabilize cooperation. A key prediction of this hypothesis that genes which are more likely be transferred, such those on should code for cooperative traits. Testing requires identifying all cooperation in bacterial genomes. However, previous studies used method misses some these To solve this, we new genomics tool, SOCfinder, uses three distinct modules identify kinds We compared where were located 4648 genomes from 146 species. In contrast the hypothesis, found no evidence plasmid Instead, opposite—that carried chromosomes. Overall, vast majority not suggesting general kin selection sufficient explain prevalence bacteria.

Language: Английский

Citations

3