Genomic comparative analysis of Ophiocordyceps unilateralis sensu lato DOI Creative Commons

Yingling Lu,

Dexiang Tang,

Zuoheng Liu

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: April 15, 2024

Ophiocordyceps unilateralis sensu lato is a common pathogenic fungus of ants. A new species, O. fusiformispora , was described based on morphology and phylogenetic evidence from five genes (SSU, LSU, TEF1α RPB1 RPB2 ). The whole genomes contiispora subtiliphialida satoi flabellata acroasca camponoti-leonardi were sequenced annotated compared with genome sequences other species in lato. basic genome-wide characteristics the 12 showed that related had similar GC content size. AntiSMASH local BLAST analyses revealed number types putative SM BGCs, NPPS, PKS, hybrid PKS-NRPS domains for differed significantly among different same genus. BGC compounds, namely, NG-391, lucilactaene, higginsianin B, pyripyropene A, pyranonigrin E excavated. NG-391 lucilactaene 7-desmethyl analogs fusarin C. Furthermore, domains, such as KS-AT-DH-MT-ER-KR-ACP SAT-KS-AT-PT-ACP-ACP-Te. ML BI trees SAT-KS-AT-PT-ACP-ACP-Te highly consistent multigene tree species. This study provided method to obtain living culture its asexual formed basis culture, which great value further future, also laid foundation analysis secondary metabolites

Language: Английский

Genomic comparative analysis of Ophiocordyceps unilateralis sensu lato DOI Creative Commons

Yingling Lu,

Dexiang Tang,

Zuoheng Liu

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: April 15, 2024

Ophiocordyceps unilateralis sensu lato is a common pathogenic fungus of ants. A new species, O. fusiformispora , was described based on morphology and phylogenetic evidence from five genes (SSU, LSU, TEF1α RPB1 RPB2 ). The whole genomes contiispora subtiliphialida satoi flabellata acroasca camponoti-leonardi were sequenced annotated compared with genome sequences other species in lato. basic genome-wide characteristics the 12 showed that related had similar GC content size. AntiSMASH local BLAST analyses revealed number types putative SM BGCs, NPPS, PKS, hybrid PKS-NRPS domains for differed significantly among different same genus. BGC compounds, namely, NG-391, lucilactaene, higginsianin B, pyripyropene A, pyranonigrin E excavated. NG-391 lucilactaene 7-desmethyl analogs fusarin C. Furthermore, domains, such as KS-AT-DH-MT-ER-KR-ACP SAT-KS-AT-PT-ACP-ACP-Te. ML BI trees SAT-KS-AT-PT-ACP-ACP-Te highly consistent multigene tree species. This study provided method to obtain living culture its asexual formed basis culture, which great value further future, also laid foundation analysis secondary metabolites

Language: Английский

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