Journal of Cell Science, Journal Year: 2023, Volume and Issue: 136(23)
Published: Dec. 1, 2023
ABSTRACT The centrosome is a non-membrane-bound organelle that conserved across most animal cells and serves various functions throughout the cell cycle. In dividing cells, known as spindle pole nucleates robust microtubule to separate genetic material equally into two daughter cells. non-dividing mother centriole, substructure of centrosome, matures basal body cilia, which acts signal-transducing antenna. centrosomes their substructures are important for embryonic development have been studied extensively using in vitro mammalian culture or vivo invertebrate models. However, there considerable differences composition during different aspects vertebrate development, these less studied. this Review, we discuss roles played by centrosomes, highlighting divergent features species, particularly fertilization development.
Language: Английский