Motifs of human hippocampal and cortical high frequency oscillations structure processing and memory of naturalistic stimuli DOI Open Access
Akash Mishra, Gelana Tostaeva, Maximilian Nentwich

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 9, 2024

Abstract The discrete events of our narrative experience are organized by the neural substrate that underlies episodic memory. This process is segmented into units event boundaries. permits a replay acts to consolidate each High frequency oscillations (HFOs) potential mechanism for synchronizing activity during these processes. Here, we use intracranial recordings from participants viewing and freely recalling naturalistic stimulus. We show hippocampal HFOs increase following boundaries coincident hippocampal-cortical (co-HFOs) occur in cortical regions previously shown underlie segmentation (inferior parietal, precuneus, lateral occipital, inferior frontal cortices). also event-specific patterns co-HFOs re-occur subsequent three (in decaying fashion) recall. consistent with models support as memory consolidation. Hence, may coordinate across brain serving widespread segmentation, encode memory, bind representations assemble coherent, continuous experience.

Language: Английский

Hippocampal sharp wave ripples and coincident cortical ripples orchestrate human semantic networks DOI Open Access
Akash Mishra, Serdar Akkol, Elizabeth Espinal

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: April 10, 2024

Abstract Episodic memory function is predicated upon the precise coordination between hippocampus and widespread cortical regions. However, our understanding of neural mechanisms involved in this process incomplete. In study, human subjects undergoing intracranial electroencephalography (iEEG) monitoring performed a list learning task. We show sharp-wave ripple (SWR)-locked reactivation specific semantic processing regions during free recall. This activation consists both broadband high frequency (non-oscillatory) (oscillatory) activity. SWRs ripples anterior temporal lobe, major hub, co-occur increase rate prior to Coincident hippocampal-ATL are associated with greater reactivation, specificity location based on recall content, preceded by theta oscillations. These findings may represent orchestrated an interplay hippocampal SWRs, ripples,

Language: Английский

Citations

4
Top-down attention shifts behavioral and neural event boundaries in narratives with overlapping event scripts DOI

Alexandra De Soares,

Tony Kim,

Franck Mugisho

et al.

Current Biology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

Citations

2
Motifs of human hippocampal and cortical high frequency oscillations structure processing and memory of naturalistic stimuli DOI Open Access
Akash Mishra, Gelana Tostaeva, Maximilian Nentwich

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 9, 2024

Abstract The discrete events of our narrative experience are organized by the neural substrate that underlies episodic memory. This process is segmented into units event boundaries. permits a replay acts to consolidate each High frequency oscillations (HFOs) potential mechanism for synchronizing activity during these processes. Here, we use intracranial recordings from participants viewing and freely recalling naturalistic stimulus. We show hippocampal HFOs increase following boundaries coincident hippocampal-cortical (co-HFOs) occur in cortical regions previously shown underlie segmentation (inferior parietal, precuneus, lateral occipital, inferior frontal cortices). also event-specific patterns co-HFOs re-occur subsequent three (in decaying fashion) recall. consistent with models support as memory consolidation. Hence, may coordinate across brain serving widespread segmentation, encode memory, bind representations assemble coherent, continuous experience.

Language: Английский

Citations

1