Amygdala Self-Neuromodulation Capacity as a Window for Process-Related Network Recruitment DOI Creative Commons
Guy Gurevitch, Nitzan Lubianiker,

Taly Markovits

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 8, 2024

Abstract Neurofeedback (NF) has emerged as a promising avenue for demonstrating process-related neuroplasticity, enabling self-regulation of brain function. NF targeting the amygdala drawn attention therapeutic potential in psychiatry, by potentially harnessing emotion-regulation processes. However, not all individuals respond equally to training, possibly due varying abilities. This underscores importance understanding mechanisms behind successful neuromodulation (i.e. capacity). study aimed investigate establishment and neural correlates capacity using data from repeated sessions Amygdala Electrical Finger Print (EFP)-NF post-training fMRI-NF session. Results 97 psychiatric patients healthy participants revealed increased amygdala-EFP over associated with fMRI modulation-capacity improvements alexithymia. Individual differences this were pre-training reactivity initial success. Additionally, down-regulation during co-modulated other regions such posterior-insula parahippocampal gyrus. combined modulation better explained EFP-modulation improvement alexithymia than alone, suggesting relevance broader network gained capacity. These findings support network-based approach highlight need consider individual function optimize interventions.

Language: Английский

Amygdala Self-Neuromodulation Capacity as a Window for Process-Related Network Recruitment DOI Creative Commons
Guy Gurevitch, Nitzan Lubianiker,

Taly Markovits

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: June 8, 2024

Abstract Neurofeedback (NF) has emerged as a promising avenue for demonstrating process-related neuroplasticity, enabling self-regulation of brain function. NF targeting the amygdala drawn attention therapeutic potential in psychiatry, by potentially harnessing emotion-regulation processes. However, not all individuals respond equally to training, possibly due varying abilities. This underscores importance understanding mechanisms behind successful neuromodulation (i.e. capacity). study aimed investigate establishment and neural correlates capacity using data from repeated sessions Amygdala Electrical Finger Print (EFP)-NF post-training fMRI-NF session. Results 97 psychiatric patients healthy participants revealed increased amygdala-EFP over associated with fMRI modulation-capacity improvements alexithymia. Individual differences this were pre-training reactivity initial success. Additionally, down-regulation during co-modulated other regions such posterior-insula parahippocampal gyrus. combined modulation better explained EFP-modulation improvement alexithymia than alone, suggesting relevance broader network gained capacity. These findings support network-based approach highlight need consider individual function optimize interventions.

Language: Английский

Citations

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