
Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: June 24, 2024
Language: Английский
Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: June 24, 2024
Language: Английский
Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)
Published: Oct. 7, 2024
Transposable elements (TEs) are mobile parasitic sequences that have expanded within the host genome. It has been hypothesized organisms Krüppel-associated box-containing zinc finger proteins (KRAB-ZFPs), which epigenetically suppress TEs, to counteract disorderly TE transpositions. This process is referred as evolutionary arms race. However, extent this race occurred across various families remains unclear. In present study, we systematically explored between and human KRAB-ZFPs using public ChIP-seq data. We discovered characterized new instances of races with in endogenous retroviruses. Furthermore, found regulatory landscape shaped by contributed gene networks. summary, our results provide insight into impact on families, KRAB-ZFP family,
Language: Английский
Citations
3bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: May 21, 2024
Abstract Transposable elements (TEs) are mobile parasitic sequences that have expanded within the host genome. It has been hypothesized organisms Krüppel-associated box-containing zinc finger proteins (KRAB-ZFPs), which epigenetically suppress TEs, to counteract disorderly TE transpositions. This process is referred as evolutionary arms race. However, extent this race occurred across various families remains unclear. In present study, we systematically explored between and KRAB-ZFPs using public ChIP-seq data. We discovered characterized new instances of races with in endogenous retroviruses. Furthermore, found regulatory landscape shaped by contributed gene network. summary, our results provide insight into impact on families, KRAB-ZFP family, networks.
Language: Английский
Citations
0Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: June 24, 2024
Language: Английский
Citations
0