Ventral Striatum is Preferentially Correlated with the Salience Network Including Regions in Dorsolateral Prefrontal Cortex DOI Creative Commons
Heather L. Kosakowski, Mark C. Eldaief, Randy L. Buckner

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 13, 2024

The ventral striatum (VS) receives input from the cerebral cortex and is modulated by midbrain dopaminergic projections in support of processing reward motivation. Here we explored organization cortical regions linked to human VS using within-individual functional connectivity MRI intensively scanned participants. In two initial participants (scanned 31 sessions each), seed were preferentially correlated with distributed that are part Salience (SAL) network. region recapitulated SAL network topography each individual including anterior posterior midline regions, insula, dorsolateral prefrontal (DLPFC) – a was distinct nearby striatal region. DLPFC positioned adjacent associated domain-flexible cognitive control. full pattern replicated independent data same individuals generalized 15 novel 8 or more each). These results suggest forms cortico-basal ganglia loop as neuromodulatory target treat major depressive disorder. present raise possibility may be an effective because its preferential coupling suggests path toward further personalization.

Language: Английский

Organization of the human cerebral cortex estimated within individuals: networks, global topography, and function DOI
Jingnan Du, Lauren M. DiNicola, Peter A. Angeli

et al.

Journal of Neurophysiology, Journal Year: 2024, Volume and Issue: 131(6), P. 1014 - 1082

Published: March 15, 2024

The organization of cerebral networks was estimated within individuals with intensive, repeat sampling fMRI data. A hierarchical emerged in each individual that delineated first-, second-, and third-order cortical networks. Regions distinct association consistently exhibited side-by-side juxtapositions repeated across multiple zones, clear robust functional specialization among the embedded regions.

Language: Английский

Citations

37

Situating the salience and parietal memory networks in the context of multiple parallel distributed networks using precision functional mapping DOI Creative Commons
Young Hye Kwon, Joseph J. Salvo, Nathan Anderson

et al.

Cell Reports, Journal Year: 2025, Volume and Issue: 44(1), P. 115207 - 115207

Published: Jan. 1, 2025

Language: Английский

Citations

2

Evidence for convergence of distributed cortical processing in band-like functional zones in human entorhinal cortex DOI Creative Commons
Daniel Reznik, Daniel S. Margulies, Menno P. Witter

et al.

Current Biology, Journal Year: 2024, Volume and Issue: 34(23), P. 5457 - 5469.e2

Published: Nov. 1, 2024

Language: Английский

Citations

5

Frequency-specific directed connectivity between the hippocampus and parietal cortex during verbal and spatial episodic memory: an intracranial EEG replication DOI
Anup Das, Vinod Menon

Cerebral Cortex, Journal Year: 2024, Volume and Issue: 34(7)

Published: July 1, 2024

Abstract Hippocampus-parietal cortex circuits are thought to play a crucial role in memory and attention, but their neural basis remains poorly understood. We employed intracranial electroencephalography (iEEG) investigate the neurophysiological underpinning of these across three tasks spanning verbal spatial domains. uncovered consistent pattern higher causal directed connectivity from hippocampus both lateral parietal (supramarginal angular gyrus) medial (posterior cingulate cortex) delta–theta band during encoding recall. This was independent activation or suppression states cortex. Crucially, supramarginal gyrus enhanced participants with recall, highlighting its behavioral significance. Our findings align attention-to-memory model, which posits that attention directs cognitive resources toward pertinent information formation. The robustness results demonstrated through Bayesian replication analysis recall periods tasks. study sheds light on casual signaling within hippocampus–parietal circuits, broadening our understanding critical roles human cognition.

Language: Английский

Citations

3

Ventral Striatum is Preferentially Correlated with the Salience Network Including Regions in Dorsolateral Prefrontal Cortex DOI Creative Commons
Heather L. Kosakowski, Mark C. Eldaief, Randy L. Buckner

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 13, 2024

The ventral striatum (VS) receives input from the cerebral cortex and is modulated by midbrain dopaminergic projections in support of processing reward motivation. Here we explored organization cortical regions linked to human VS using within-individual functional connectivity MRI intensively scanned participants. In two initial participants (scanned 31 sessions each), seed were preferentially correlated with distributed that are part Salience (SAL) network. region recapitulated SAL network topography each individual including anterior posterior midline regions, insula, dorsolateral prefrontal (DLPFC) – a was distinct nearby striatal region. DLPFC positioned adjacent associated domain-flexible cognitive control. full pattern replicated independent data same individuals generalized 15 novel 8 or more each). These results suggest forms cortico-basal ganglia loop as neuromodulatory target treat major depressive disorder. present raise possibility may be an effective because its preferential coupling suggests path toward further personalization.

Language: Английский

Citations

1