Aberrant auditory prediction patterns robustly characterize tinnitus DOI Creative Commons
Lisa Reisinger, Gianpaolo Demarchi, Jonas Obleser

et al.

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Dec. 30, 2024

Phantom perceptions like tinnitus occur without any identifiable environmental or bodily source. The mechanisms and key drivers behind are poorly understood. dominant framework, suggesting that results from neural hyperactivity in the auditory pathway following hearing damage, has been difficult to investigate humans reached explanatory limits. As a result, researchers have tried explain perceptual potential aberrations within more parsimonious predictive-coding framework. In two independent magnetoencephalography studies, participants passively listened sequences of pure tones with varying levels regularity (i.e. predictability) ranging random ordered. Aside being replication first study, pre-registered second including 80 participants, ensured rigorous matching status, as well age, sex, loss, between individuals tinnitus. Despite some changes details paradigm, both studies equivalently reveal group difference representation, based on multivariate pattern analysis, upcoming stimuli before their onset. These data strongly suggest engage anticipatory predictions differently controls. While observation different predictive processes is robust replicable, precise neurocognitive mechanism underlying it calls for further, ideally longitudinal, establish its role contributor to, and/or consequence of,

Language: Английский

Intensity mismatch asymmetry in tinnitus – in which direction should participants pay attention? DOI Creative Commons
Ekaterina A Yukhnovich, Kai Alter, William Sedley

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 3, 2024

Abstract The effects attention has on intensity deviant Mismatch Negativity responses is an unknown factor in basic sensory neuroscience. It would be useful to understand how affect deviants compared each other (upward vs downward), and dimensions such as frequency. Overall, previous research indicates that may modulate neuronal gain healthy participants change the amplitudes of evoked responses, mainly regularly repeating (standard) stimuli rather than deviants. Gain respond differently with tinnitus and/or hyperacusis under same conditions controls. results passive task condition were consistent research. Auditory magnified MMN response upward deviants, while visual attenuated it both control groups. However, auditory selectively enhanced downward group (compared attention). Using paradigm advantageous studies tinnitus/hyperacusis because observed differences particularly large.

Language: Английский

Citations

2
Aberrant auditory prediction patterns robustly characterize tinnitus DOI Creative Commons
Lisa Reisinger, Gianpaolo Demarchi, Jonas Obleser

et al.

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Aug. 27, 2024

Phantom perceptions like tinnitus occur without any identifiable environmental or bodily source. The mechanisms and key drivers behind are poorly understood. dominant framework, suggesting that results from neural hyperactivity in the auditory pathway following hearing damage, has been difficult to investigate humans reached explanatory limits. As a result, researchers have tried explain perceptual potential aberrations within more parsimonious predictive-coding framework. In two independent magnetoencephalography studies, participants passively listened sequences of pure tones with varying levels regularity (i.e. predictability) ranging random ordered. Aside being replication first study, pre-registered second including 80 participants, ensured rigorous matching status, as well age, sex, loss, between individuals tinnitus. Despite some changes details paradigm, both studies equivalently reveal group difference representation, based on multivariate pattern analysis, upcoming stimuli before their onset. These data strongly suggest engage anticipatory predictions differently controls. While observation different predictive processes is robust replicable, precise neurocognitive mechanism underlying it calls for further, ideally longitudinal, establish its role contributor to, and/or consequence of,

Language: Английский

Citations

1
Aberrant Auditory Prediction Patterns Robustly Characterize Tinnitus DOI Open Access
Lisa Reisinger, Gianpaolo Demarchi, Jonas Obleser

et al.

Published: May 15, 2024

Phantom perceptions like tinnitus occur without any identifiable environmental orbodily source. The mechanisms and key drivers behind are poorly understood. dominant framework, suggesting that results from neural hyperactivity in the auditory pathway following hearing damage, has been difficult to investigate humans reached explanatory limits. As a result, researchers have tried explain perceptual potential aberrations within more parsimonious predictive-coding framework. In two independent magnetoencephalography (MEG) studies, participants passively listened sequences of pure tones with varying levels regularity (i.e. predictability) ranging random ordered. Aside being replication first study, pre- registered second including 80 participants, ensured rigorous matching status, as well age, sex, loss, between individuals tinnitus. Despite some changes details paradigm, both studies equivalently reveal group difference representation, based on multivariate pattern analysis, upcoming stimuli before their onset. These data strongly suggest engage anticipatory predictions differently controls. While observation different predictive processes is robust replicable, precise neurocognitive mechanism underlying it calls for further, ideally longitudinal, establish its role contributor to, and/or consequence of, tinnitus.Keywords: perceptions, tinnitus, coding, MEG

Language: Английский

Citations

0
Aberrant Auditory Prediction Patterns Robustly Characterize Tinnitus DOI Open Access
Lisa Reisinger, Gianpaolo Demarchi, Jonas Obleser

et al.

Published: Aug. 27, 2024

Phantom perceptions like tinnitus occur without any identifiable environmental or bodily source. The mechanisms and key drivers behind are poorly understood. dominant framework, suggesting that results from neural hyperactivity in the auditory pathway following hearing damage, has been difficult to investigate humans reached explanatory limits. As a result, researchers have tried explain perceptual potential aberrations within more parsimonious predictive-coding framework. In two independent magnetoencephalography (MEG) studies, participants passively listened sequences of pure tones with varying levels regularity (i.e. predictability) ranging random ordered. Aside being replication first study, pre-registered second including 80 participants, ensured rigorous matching status, as well age, sex, loss, between individuals tinnitus. Despite some changes details paradigm, both studies equivalently reveal group difference representation, based on multivariate pattern analysis, upcoming stimuli before their onset. These data strongly suggest engage anticipatory predictions differently controls. While observation different predictive processes is robust replicable, precise neurocognitive mechanism underlying it calls for further, ideally longitudinal, establish its role contributor to, and/or consequence of,

Language: Английский

Citations

0
Aberrant Auditory Prediction Patterns Robustly Characterize Tinnitus DOI Open Access
Lisa Reisinger, Gianpaolo Demarchi, Jonas Obleser

et al.

Published: Nov. 29, 2024

Phantom perceptions like tinnitus occur without any identifiable environmental or bodily source. The mechanisms and key drivers behind are poorly understood. dominant framework, suggesting that results from neural hyperactivity in the auditory pathway following hearing damage, has been difficult to investigate humans reached explanatory limits. As a result, researchers have tried explain perceptual potential aberrations within more parsimonious predictive-coding framework. In two independent magnetoencephalography (MEG) studies, participants passively listened sequences of pure tones with varying levels regularity (i.e. predictability) ranging random ordered. Aside being replication first study, pre-registered second including 80 participants, ensured rigorous matching status, as well age, sex, loss, between individuals tinnitus. Despite some changes details paradigm, both studies equivalently reveal group difference representation, based on multivariate pattern analysis, upcoming stimuli before their onset. These data strongly suggest engage anticipatory predictions differently controls. While observation different predictive processes is robust replicable, precise neurocognitive mechanism underlying it calls for further, ideally longitudinal, establish its role contributor to, and/or consequence of,

Language: Английский

Citations

0
What Do Mismatch Negativity (MMN) Responses Tell Us About Tinnitus? DOI Creative Commons
Ekaterina A Yukhnovich, Kai Alter, William Sedley

et al.

Journal of the Association for Research in Otolaryngology, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 16, 2024

Language: Английский

Citations

0
Aberrant Auditory Prediction Patterns Robustly Characterize Tinnitus DOI Open Access
Lisa Reisinger, Gianpaolo Demarchi, Jonas Obleser

et al.

Published: Dec. 16, 2024

Phantom perceptions like tinnitus occur without any identifiable environmental or bodily source. The mechanisms and key drivers behind are poorly understood. dominant framework, suggesting that results from neural hyperactivity in the auditory pathway following hearing damage, has been difficult to investigate humans reached explanatory limits. As a result, researchers have tried explain perceptual potential aberrations within more parsimonious predictive-coding framework. In two independent magnetoencephalography (MEG) studies, participants passively listened sequences of pure tones with varying levels regularity (i.e. predictability) ranging random ordered. Aside being replication first study, pre-registered second including 80 participants, ensured rigorous matching status, as well age, sex, loss, between individuals tinnitus. Despite some changes details paradigm, both studies equivalently reveal group difference representation, based on multivariate pattern analysis, upcoming stimuli before their onset. These data strongly suggest engage anticipatory predictions differently controls. While observation different predictive processes is robust replicable, precise neurocognitive mechanism underlying it calls for further, ideally longitudinal, establish its role contributor to, and/or consequence of,

Language: Английский

Citations

0
Aberrant auditory prediction patterns robustly characterize tinnitus DOI Creative Commons
Lisa Reisinger, Gianpaolo Demarchi, Jonas Obleser

et al.

eLife, Journal Year: 2024, Volume and Issue: 13

Published: Dec. 30, 2024

Phantom perceptions like tinnitus occur without any identifiable environmental or bodily source. The mechanisms and key drivers behind are poorly understood. dominant framework, suggesting that results from neural hyperactivity in the auditory pathway following hearing damage, has been difficult to investigate humans reached explanatory limits. As a result, researchers have tried explain perceptual potential aberrations within more parsimonious predictive-coding framework. In two independent magnetoencephalography studies, participants passively listened sequences of pure tones with varying levels regularity (i.e. predictability) ranging random ordered. Aside being replication first study, pre-registered second including 80 participants, ensured rigorous matching status, as well age, sex, loss, between individuals tinnitus. Despite some changes details paradigm, both studies equivalently reveal group difference representation, based on multivariate pattern analysis, upcoming stimuli before their onset. These data strongly suggest engage anticipatory predictions differently controls. While observation different predictive processes is robust replicable, precise neurocognitive mechanism underlying it calls for further, ideally longitudinal, establish its role contributor to, and/or consequence of,

Language: Английский

Citations

0