Detection of idiosyncratic gaze fingerprint signatures in humans DOI Creative Commons
Sarah K. Crockford, Eleonora Satta, Ines Severino

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 18, 2023

Abstract Variation in human gaze can be explained by a variety of factors. Within an individual, patterns quite reliable and part heritable common genetic mechanisms. If individual are strongly idiosyncratic, could they enable highly accurate detection individuals via ‘gaze fingerprint’? And fingerprints linked to variation phenotypes such as autistic traits, which underpinned mechanisms cause atypical idiosyncratic manifest early development? To answer these questions we utilized stimulus-rich design where participants viewed 700 stimuli complex natural scenes, repeated two sessions separated ∼1-2 weeks. Across independent discovery (n=105) replication (n=46) datasets, find that fingerprinting occurs at high rates (52-63%) relative chance (1-2%) when similarity is averaged across stimuli. However, averaging procedures hide unique non-random individuating code represented multivariate fingerprint barcode’ pattern all barcodes, around 91-95% had fingerprintable counts were significantly higher than situations identity randomly permuted. Data-driven clustering barcodes results each its own cluster. Finally, increased fingerprintability’ associated with decreased levels traits. Overall, this work showcases strong potential for on large-scale data well translational relevance conditions autism.

Language: Английский

Detection of idiosyncratic gaze fingerprint signatures in humans DOI Creative Commons
Sarah K. Crockford, Eleonora Satta, Ines Severino

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 18, 2023

Abstract Variation in human gaze can be explained by a variety of factors. Within an individual, patterns quite reliable and part heritable common genetic mechanisms. If individual are strongly idiosyncratic, could they enable highly accurate detection individuals via ‘gaze fingerprint’? And fingerprints linked to variation phenotypes such as autistic traits, which underpinned mechanisms cause atypical idiosyncratic manifest early development? To answer these questions we utilized stimulus-rich design where participants viewed 700 stimuli complex natural scenes, repeated two sessions separated ∼1-2 weeks. Across independent discovery (n=105) replication (n=46) datasets, find that fingerprinting occurs at high rates (52-63%) relative chance (1-2%) when similarity is averaged across stimuli. However, averaging procedures hide unique non-random individuating code represented multivariate fingerprint barcode’ pattern all barcodes, around 91-95% had fingerprintable counts were significantly higher than situations identity randomly permuted. Data-driven clustering barcodes results each its own cluster. Finally, increased fingerprintability’ associated with decreased levels traits. Overall, this work showcases strong potential for on large-scale data well translational relevance conditions autism.

Language: Английский

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