Neural substrates and behavioral relevance of speech envelope tracking: evidence from post-stroke aphasia DOI Creative Commons
Pieter De Clercq, Jill Kries, Jonas Vanthornhout

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: March 28, 2024

Abstract Neural tracking of the low-frequency temporal envelope speech has emerged as a prominent tool to investigate neural mechanisms natural processing in brain. However, there is ongoing debate regarding functional role tracking. In this context, our study aims offer novel perspective by investigating critical brain areas and behavioral skills required for aphasia, language disorder characterized impaired We analyzed an EEG dataset 39 individuals with post-stroke aphasia suffering left-hemispheric stroke who listened speech. Our analysis involved lesion mapping, where left lesioned voxels served binary features predict measures. also examined correlates receptive language, naming, auditory (via rise time discrimination task) skills. The mapping revealed that lesions areas, such middle gyrus, supramarginal gyrus angular were associated poorer Additionally, was related (receptive naming) effects on less robust, possibly due ceiling scores. findings highlight importance central implicated understanding, extending beyond primary cortex, emphasize intact abilities effectively Collectively, these underscore significance mere audibility acoustic processes. Significance statement While some studies have proposed primarily relates processes, others suggested its involvement actual comprehension. By essential we argue broader processing. Furthermore, specificity among indicating correlation regions functions. This addresses significant heterogeneity characteristics present suggests potential EEG-based specifically assessing population.

Language: Английский

Neural substrates and behavioral relevance of speech envelope tracking: evidence from post-stroke aphasia DOI Creative Commons
Pieter De Clercq, Jill Kries, Jonas Vanthornhout

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: March 28, 2024

Abstract Neural tracking of the low-frequency temporal envelope speech has emerged as a prominent tool to investigate neural mechanisms natural processing in brain. However, there is ongoing debate regarding functional role tracking. In this context, our study aims offer novel perspective by investigating critical brain areas and behavioral skills required for aphasia, language disorder characterized impaired We analyzed an EEG dataset 39 individuals with post-stroke aphasia suffering left-hemispheric stroke who listened speech. Our analysis involved lesion mapping, where left lesioned voxels served binary features predict measures. also examined correlates receptive language, naming, auditory (via rise time discrimination task) skills. The mapping revealed that lesions areas, such middle gyrus, supramarginal gyrus angular were associated poorer Additionally, was related (receptive naming) effects on less robust, possibly due ceiling scores. findings highlight importance central implicated understanding, extending beyond primary cortex, emphasize intact abilities effectively Collectively, these underscore significance mere audibility acoustic processes. Significance statement While some studies have proposed primarily relates processes, others suggested its involvement actual comprehension. By essential we argue broader processing. Furthermore, specificity among indicating correlation regions functions. This addresses significant heterogeneity characteristics present suggests potential EEG-based specifically assessing population.

Language: Английский

Citations

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