bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: March 20, 2024
Abstract Three major empirical patterns involving sex chromosomes have been observed in higher eukaryotes: Y (or W) are often non-recombining and degenerate; when two species hybridize, but one is sterile or inviable among hybrid offspring, it most the heterogametic (XY ZW)—the so-called Haldane’s rule; X Z) plays a disproportionately large effect on reproductive isolation compared to autosomes—the effect. Each observation has generally received its own tailored explanation multiple genetic evolutionary causes 1–3 . Here, we show that these all emerge from single theory for chromosome evolution incorporating co-evolution of cis trans-acting regulators gene expression, leading systematic rapid misexpression dosage-compensated genes F1 hybrids, young old sex-chromosomes. This links post-zygotic hybrids.
Language: Английский