
IJID Regions, Journal Year: 2024, Volume and Issue: 14, P. 100503 - 100503
Published: Dec. 4, 2024
Objectives: The SARS-CoV-2 JN.1 lineage emerged in late 2023 and quickly replaced the XBB lineages, becoming predominant Omicron variant worldwide 2024. We estimate epidemiologic impact of this replacement Brazil we further assessed cross-reactive neutralizing antibody (NAb) responses a cohort convalescent Brazilian patients infected during 2023. analyzed evolution lineages severe acute respiratory infection (SARI) cases between July March evaluated NAb to before after with XBB.1* lineages. similar temporal dynamics across all country regions, although its varied locations. southeastern, southern, central-western regions experienced brief wave around October 2023, shortly introduction JN.1, without any immediate upsurge SARI viral replacement. By contrast, northeastern northern did not experience an latter half displayed rapid surge driven by emergence JN.1. found that recent infections population significantly boosted levels against observed second some states likely acted as booster for immunity, providing short-term protection delaying rise certain country.
Language: Английский