Impacts of pleiotropy and migration on repeated genetic adaptation DOI Creative Commons
Paul Battlay, Sam Yeaman, Kathryn A. Hodgins

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2021, Volume and Issue: unknown

Published: Sept. 13, 2021

Abstract Observations of genetically repeated evolution (repeatability) in complex organisms are incongruent with the Fisher-Orr model, which implies that use same gene should be rare when mutations pleiotropic (i.e., affect multiple traits). When spatially divergent selection occurs presence migration, large effect more strongly favoured, and hence repeatability is likely, but it unclear whether this observation limited by pleiotropy. Here, we explore question using individual-based simulations a two-patch model incorporating quantitative traits governed effects. We relationship between fitness trade-offs varying alignment mutation spatial variation trait optima. While decreases increasing dimensionality, effects on do not limit contribution locus to adaptation, particularly under increased migration. These results suggest will pronounced for local rather than global adaptation. Whereas pleiotropy limits single-population there adaptation flow, can occur if some loci able produce alleles effect, even trade-offs. Article summary Classical evolutionary theory predicts vanishingly where traits. In article, study such mutations, their two patches selection. find migration increases likelihood evolution, imposed

Language: Английский

The genomic secrets of invasive plants DOI Open Access
Kathryn A. Hodgins, Paul Battlay, Dan G. Bock

et al.

New Phytologist, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Summary Genomics has revolutionised the study of invasive species, allowing evolutionary biologists to dissect mechanisms invasion in unprecedented detail. Botanical research played an important role these advances, driving much what we currently know about key determinants success (e.g. hybridisation, whole‐genome duplication). Despite this, a comprehensive review plant genomics been lacking. Here, aim address this gap, highlighting recent discoveries that have helped progress field. For example, by leveraging natural and experimental populations, botanical confirmed importance large‐effect standing variation during adaptation species. Further, genomic investigations plants are increasingly revealing large structural variants, as well genetic changes induced duplication such redundancy or breakdown dosage‐sensitive reproductive barriers, can play adaptive evolution invaders. However, numerous questions remain, including when chromosomal inversions might help hinder invasions, whether gene reuse is common epigenetically mutations underpin plasticity populations. We conclude other outstanding studies poised answer.

Language: Английский

Citations

1
Eco-evolutionary dynamics in changing environments: integrating theory with data DOI

Louise Fouqueau,

Jitka Polechová

Journal of Evolutionary Biology, Journal Year: 2024, Volume and Issue: 37(6), P. 579 - 587

Published: June 1, 2024

Language: Английский

Citations

0
Impacts of pleiotropy and migration on repeated genetic adaptation DOI Creative Commons
Paul Battlay, Sam Yeaman, Kathryn A. Hodgins

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2021, Volume and Issue: unknown

Published: Sept. 13, 2021

Abstract Observations of genetically repeated evolution (repeatability) in complex organisms are incongruent with the Fisher-Orr model, which implies that use same gene should be rare when mutations pleiotropic (i.e., affect multiple traits). When spatially divergent selection occurs presence migration, large effect more strongly favoured, and hence repeatability is likely, but it unclear whether this observation limited by pleiotropy. Here, we explore question using individual-based simulations a two-patch model incorporating quantitative traits governed effects. We relationship between fitness trade-offs varying alignment mutation spatial variation trait optima. While decreases increasing dimensionality, effects on do not limit contribution locus to adaptation, particularly under increased migration. These results suggest will pronounced for local rather than global adaptation. Whereas pleiotropy limits single-population there adaptation flow, can occur if some loci able produce alleles effect, even trade-offs. Article summary Classical evolutionary theory predicts vanishingly where traits. In article, study such mutations, their two patches selection. find migration increases likelihood evolution, imposed

Language: Английский

Citations

1