Living on the edge: Mucus-associated microbes in the colon DOI Creative Commons
Mihovil Joja, Erica T. Grant, Mahesh S. Desai

et al.

Mucosal Immunology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

The colonic mucus layer acts as a physicochemical barrier to pathogen invasion and habitat for mucus-associated microbes. This mucosal microbiome plays crucial role in moderating production, maintaining integrity, shaping the host immune response. However, unchecked mucin foraging may render vulnerable disease. To better understand these dynamics layer, it is essential advance fundamental knowledge on how commensals bind utilize well their interactions with both microbial neighbors. We present an overview of approaches surveying bacteria assessing mucin-utilizing capacity, alongside discussion limitations existing methods. Additionally, we highlight diet secretory immunoglobulin A interact bacterial community colon. Insights into this subset can guide therapeutic strategies optimally support modulate integrity.

Language: Английский

Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research DOI
Thomas Clavel, Franziska Faber, Mathieu Groussin

et al.

Nature Biotechnology, Journal Year: 2025, Volume and Issue: unknown

Published: April 29, 2025

Language: Английский

Citations

0
Living on the edge: Mucus-associated microbes in the colon DOI Creative Commons
Mihovil Joja, Erica T. Grant, Mahesh S. Desai

et al.

Mucosal Immunology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

The colonic mucus layer acts as a physicochemical barrier to pathogen invasion and habitat for mucus-associated microbes. This mucosal microbiome plays crucial role in moderating production, maintaining integrity, shaping the host immune response. However, unchecked mucin foraging may render vulnerable disease. To better understand these dynamics layer, it is essential advance fundamental knowledge on how commensals bind utilize well their interactions with both microbial neighbors. We present an overview of approaches surveying bacteria assessing mucin-utilizing capacity, alongside discussion limitations existing methods. Additionally, we highlight diet secretory immunoglobulin A interact bacterial community colon. Insights into this subset can guide therapeutic strategies optimally support modulate integrity.

Language: Английский

Citations

0