Sex-Specific Dominance of Gene Expression in Seed Beetles DOI Creative Commons
Philipp Kaufmann, Johanna Rönn, Elina Immonen

et al.

Molecular Biology and Evolution, Journal Year: 2024, Volume and Issue: 41(12)

Published: Dec. 1, 2024

Abstract When different alleles are favored in environments, dominance reversal where alternate dominant the environment which they can generate net balancing selection. The sexes represent two distinct genetic environments and sexually antagonistic (SA) selection maintain variation, especially when involved show sex-specific dominance. Sexual dimorphism gene expression is pervasive has been suggested to result from SA Yet, whether gene-regulatory variation shows poorly understood. We tested for using three crosses between homozygous lines derived a population of seed beetle, previous study documented signal fitness sexes. Overall, we found that effects variants affecting were positively correlated (r = 0.33 0.44). 586 transcripts showed significant differences Sex-specific was significantly more common with sex-biased expression, our crosses. Among showing dominance, lesser sexual among heterozygotes somewhat than greater. Gene ontology enrichment analyses functional categories associated known phenotypes Callosobruchus maculatus overrepresented including genes metabolic processes target-of-rapamycin pathway. Our results support suggestion regulatory contributes maintenance mediated by this species.

Language: Английский

Sex-Specific Dominance of Gene Expression in Seed Beetles DOI Creative Commons
Philipp Kaufmann, Johanna Rönn, Elina Immonen

et al.

Molecular Biology and Evolution, Journal Year: 2024, Volume and Issue: 41(12)

Published: Dec. 1, 2024

Abstract When different alleles are favored in environments, dominance reversal where alternate dominant the environment which they can generate net balancing selection. The sexes represent two distinct genetic environments and sexually antagonistic (SA) selection maintain variation, especially when involved show sex-specific dominance. Sexual dimorphism gene expression is pervasive has been suggested to result from SA Yet, whether gene-regulatory variation shows poorly understood. We tested for using three crosses between homozygous lines derived a population of seed beetle, previous study documented signal fitness sexes. Overall, we found that effects variants affecting were positively correlated (r = 0.33 0.44). 586 transcripts showed significant differences Sex-specific was significantly more common with sex-biased expression, our crosses. Among showing dominance, lesser sexual among heterozygotes somewhat than greater. Gene ontology enrichment analyses functional categories associated known phenotypes Callosobruchus maculatus overrepresented including genes metabolic processes target-of-rapamycin pathway. Our results support suggestion regulatory contributes maintenance mediated by this species.

Language: Английский

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