A latitudinal gradient of reference genomes DOI Creative Commons
Ethan Linck, Carlos Daniel Cadena

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 13, 2024

Abstract Global inequality rooted in legacies of colonialism and uneven development can lead to systematic biases scientific knowledge. In ecology evolutionary biology, findings, funding research effort are disproportionately concentrated at high latitudes while biological diversity is low latitudes. This discrepancy may have a particular influence fields like phylogeography, molecular conservation genetics, where the rise genomics has increased cost technical expertise required apply state-of-the-art methods. Here we ask whether fundamental biogeographic pattern—the latitudinal gradient species richness tetrapods—is reflected available reference genomes, an important data resource for various applications tools biodiversity conservation. We also sequencing approaches differ between South North, reviewing last five years genetics four leading journals. find that extant genomes scarce relative latitudes, reduced-representation whole-genome applied taxa North. conclude with recommendations close this gap improve international collaborations genomics.

Language: Английский

The Amphibian Major Histocompatibility Complex—A Review and Future Outlook DOI Creative Commons
Joana Sabino‐Pinto, Martine E. Maan

Journal of Molecular Evolution, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

Abstract The major histocompatibility complex (MHC) is a cluster of functionally related genes encoding proteins which, among other functions, mediate immune system activation. While the MHC many vertebrates has been extensively studied, less known about amphibian MHC. This represents an important knowledge gap because amphibians mark evolutionary transition from aquatic to terrestrial lifestyle and often maintain biphasic lifestyle. Hence, they tend be exposed both pathogen communities, providing opportunities gain fundamental insights into how responds different environmental challenges. Moreover, are globally threatened by invasive pathogens may play role in combating population decline. In this review, we summarize current state regarding identify differences with vertebrates. We also review number gene copies varies across groups MHC-based variation relates ontogeny, behaviour, disease, phylogeography. conclude identifying gaps proposing priorities for future research.

Language: Английский

Citations

0
A Latitudinal Gradient of Reference Genomes DOI Creative Commons
Ethan Linck, Carlos Daniel Cadena

Molecular Ecology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 14, 2024

ABSTRACT Global inequality rooted in legacies of colonialism and uneven development can lead to systematic biases scientific knowledge. In ecology evolutionary biology, findings, funding research effort are disproportionately concentrated at high latitudes, while biological diversity is low latitudes. This discrepancy may have a particular influence fields like phylogeography, molecular conservation genetics, where the rise genomics has increased cost technical expertise required apply state‐of‐the‐art methods. Here, we ask whether fundamental biogeographic pattern—the latitudinal gradient species richness tetrapods—is reflected available reference genomes, an important data resource for various applications tools biodiversity conservation. We also sequencing approaches differ between South North, reviewing last 5 years genetics four leading journals. find that extant genomes scarce relative latitudes reduced representation whole‐genome applied taxa North. conclude with recommendations close this gap improve international collaborations genomics.

Language: Английский

Citations

2
A latitudinal gradient of reference genomes DOI Creative Commons
Ethan Linck, Carlos Daniel Cadena

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 13, 2024

Abstract Global inequality rooted in legacies of colonialism and uneven development can lead to systematic biases scientific knowledge. In ecology evolutionary biology, findings, funding research effort are disproportionately concentrated at high latitudes while biological diversity is low latitudes. This discrepancy may have a particular influence fields like phylogeography, molecular conservation genetics, where the rise genomics has increased cost technical expertise required apply state-of-the-art methods. Here we ask whether fundamental biogeographic pattern—the latitudinal gradient species richness tetrapods—is reflected available reference genomes, an important data resource for various applications tools biodiversity conservation. We also sequencing approaches differ between South North, reviewing last five years genetics four leading journals. find that extant genomes scarce relative latitudes, reduced-representation whole-genome applied taxa North. conclude with recommendations close this gap improve international collaborations genomics.

Language: Английский

Citations

0