Morphological simulation tests the limits on phenotype discovery in 3D image analysis DOI
Rachel A. Roston, Sophie M. Whikehart, Sara Rolfe

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 2, 2024

In the past few decades, advances in 3D imaging have created new opportunities for reverse genetic screens. Rapidly growing datasets of images knockouts require high-throughput, automated computational approaches identifying and characterizing phenotypes. However, exploratory, discovery-oriented image analysis pipelines used to discover these phenotypes can be difficult validate because, by their nature, expected outcome is not known

Language: Английский

Morphological simulation tests the limits on phenotype discovery in 3D image analysis DOI
Rachel A. Roston, Sophie M. Whikehart, Sara Rolfe

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: July 2, 2024

In the past few decades, advances in 3D imaging have created new opportunities for reverse genetic screens. Rapidly growing datasets of images knockouts require high-throughput, automated computational approaches identifying and characterizing phenotypes. However, exploratory, discovery-oriented image analysis pipelines used to discover these phenotypes can be difficult validate because, by their nature, expected outcome is not known

Language: Английский

Citations

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