Journal of Nanobiotechnology, Journal Year: 2024, Volume and Issue: 22(1)

Published: Oct. 4, 2024

Abstract Glioblastomas (GBMs) are the most common and aggressive malignant brain tumors, presenting significant challenges for treatment due to their invasive nature localization in critical regions. Standard includes surgical resection followed by radiation adjuvant chemotherapy with temozolomide (TMZ). Recent advances immunotherapy, including use of mRNA vaccines, offer promising alternatives. This review focuses on emerging vaccines GBM treatment. We summarize recent advancements, evaluate current obstacles, discuss notable successes this field. Our analysis highlights that while have shown potential, is still experimental. Ongoing research clinical trials essential fully understand therapeutic potential. Future developments vaccine technology insights into GBM-specific immune responses may lead more targeted effective treatments. Despite promise, further crucial validate optimize effectiveness combating GBM. Graphical

Language: Английский