Bacteriophage resistance increases bacterial productivity by shifting population growth dynamics in the soil bacteriumVariovoraxsp DOI Creative Commons
Meaghan Castledine, Daniel Padfield,

Rai Lewis

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: March 7, 2024

Abstract Lytic bacteriophages (‘phages’) can limit bacterial densities, either directly through lysis or indirectly costs to resistance. However, phages have also been reported no, and in some cases even positive, effects on host densities. Here, we investigate the mechanisms behind an increase density Variovorax sp. populations following a fixation of resistance that was maintained after phage extinction. Our results demonstrate genetic trait coinciding with emergence. Growth curves showed shifted population growth such higher death-phase. This density-increasing effect had important implications for community structure resistant decreasing conspecific. That lytic densities has wider ecology therapy where are presumed negative their hosts.

Language: Английский

Bacteriophage resistance increases bacterial productivity by shifting population growth dynamics in the soil bacteriumVariovoraxsp DOI Creative Commons
Meaghan Castledine, Daniel Padfield,

Rai Lewis

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: March 7, 2024

Abstract Lytic bacteriophages (‘phages’) can limit bacterial densities, either directly through lysis or indirectly costs to resistance. However, phages have also been reported no, and in some cases even positive, effects on host densities. Here, we investigate the mechanisms behind an increase density Variovorax sp. populations following a fixation of resistance that was maintained after phage extinction. Our results demonstrate genetic trait coinciding with emergence. Growth curves showed shifted population growth such higher death-phase. This density-increasing effect had important implications for community structure resistant decreasing conspecific. That lytic densities has wider ecology therapy where are presumed negative their hosts.

Language: Английский

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