Trends in Cell Biology, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
The 3D folding of the genome is tightly linked to its epigenetic state which maintains gene expression programmes. Although relationship between and organisation highly context dependent, emerging as a novel layer reinforce stabilise transcriptional states. Whether regulatory information carried in could be transmitted through mitosis an area active investigation. In this review, we discuss nuclear organisation, well interplay regulation folding. We also consider architectural remodelling nuclei cells enter exit mitosis, evaluate potential contribute cellular memory.
Language: Английский