Enhanced Axial Resolution in Dermascopy using Broadband RGB Flat Lens DOI Creative Commons
Aqeel ur Rehman,

Ramna Khalid,

Isma Javed

et al.

Optical Materials Express, Journal Year: 2024, Volume and Issue: 14(11), P. 2623 - 2623

Published: Oct. 9, 2024

Dermoscopy is a diagnostic tool in biomedical science, enabling non-invasive, high-resolution imaging for early detection and diagnosis of skin diseases. Although there have been considerable improvements functionality applications dermoscopy, enhancement depth-of-focus (DOF) detailed multiple layers needs to be addressed. High axial length improves the function by providing more comprehensive understanding subsurface structures abnormalities. We proposed flat lens solution enhanced resolution that aids differentiating between benign malignant lesions, improving accuracy patient outcomes. This study presents an all-dielectric design metalens, which uses titanium dioxide (TiO 2 ) simultaneously achieve maximum transmission extended resolution. Our designed metalens are optimized broadband visible light regimes from 488 nm 633 nm, offering performance across this broad spectral range. Using (EDOF) has enabled healthcare experts substantially enhance dermoscopy. results ability scan dermis epidermis real time diagnosis. technology integration into medical engineering increases real-time diagnostics, improved dermoscopy examinations.

Language: Английский

Ultra-compact quintuple-band terahertz metamaterial biosensor for enhanced blood cancer diagnostics DOI Creative Commons
Musa N. Hamza, Mohammad Tariqul Islam, Sunil Lavadiya

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(1), P. e0313874 - e0313874

Published: Jan. 9, 2025

Cancer and its diverse variations pose one of the most significant threats to human health well-being. One aggressive forms is blood cancer, originating from bone marrow cells disrupting production normal cells. The incidence cancer steadily increasing, driven by both genetic environmental factors. Therefore, early detection crucial as it enhances treatment outcomes improves success rates. However, accurate diagnosis challenging due inherent similarities between cancerous Although various techniques are available for identification, high-frequency imaging have recently shown promise, particularly real-time monitoring. Notably, terahertz (THz) frequencies offer unique advantages biomedical applications. This research proposes an innovative metamaterial-based biosensor high-efficacy detection. proposed structure ultra-compact operates across five bands within range 0.6 1.2 THz. It constructed using a polyethylene terephthalate (PET) dielectric layer two aluminum (Al) layers, with top serving base THz-range resonator. Careful design, architectural arrangement, optimization geometry parameters allow achieving nearly perfect absorption rates (>95%) all operating bands. properties sensor extensively evaluated through full-wave electromagnetic (EM) analysis, which includes assessing refractive index distribution electric field at individual working frequencies. suitability has been validated integrating into microwave (MWI) system conducting comprehensive simulation studies. These studies underscore device’s capability detect abnormalities, in distinguishing healthy Benchmarking against state-of-the-art biosensors recent literature indicates that highly competitive terms major performance indicators while maintaining compact size.

Language: Английский

Citations

4
Nano biosensors: Classification, electrochemistry, nanostructures, and optical properties DOI Creative Commons
Ahmed Mahdi Rheima, Zainab T. Al‐Sharify, Ameen Alwan Mohaimeed

et al.

Results in Engineering, Journal Year: 2024, Volume and Issue: unknown, P. 103428 - 103428

Published: Nov. 1, 2024

Language: Английский

Citations

7
Design and Analysis of a Highly Sensitive Terahertz Biosensor for Early Cancer Detection Using Silver Surface Plasmon Resonance Metasurfaces and Elastic Reflection Starling Murmuration Equivariant Quantum Decision Networks DOI Creative Commons

M. Karthikeyan,

R. Dhivya,

C. N. Sangeetha

et al.

ECS Journal of Solid State Science and Technology, Journal Year: 2025, Volume and Issue: 14(1), P. 017003 - 017003

Published: Jan. 1, 2025

Terahertz (THz) biosensors have emerged as a promising technology for medical diagnostics, particularly cancer detection, due to their unique capability interact with biological tissues at the molecular level. This research presents novel THz biosensor design that combines silver-based surface plasmon resonance metasurfaces sophisticated neural network architecture, termed elastic reflection starling murmuration equivariant quantum decision network. By leveraging networks and integrating them an transformer, this enhances sensitivity specificity of detection by capturing subtle biomolecular interactions. The optimizer extends process, tweaking tuning parameters avoid many false alarms possible obtain exactly correct resonant shift each biomarker change. Its high sensitivity, combined quantum-inspired makes platform increasing early diagnostics tumors compared traditional approaches. model also delivers classifying approximately 99.8%. suggested structure’s can be enhanced up 275 GHz RIU −1 FOM 3.05 Q factor 11.85. proposed architecture shows potential scalable applications in clinical settings, aiding timely diagnosis potentially improving patient outcomes.

Language: Английский

Citations

0
Design and validation of ultra-compact metamaterial-based biosensor for non-invasive cervical cancer diagnosis in terahertz regime DOI Creative Commons
Musa N. Hamza, Mohammad Tariqul Islam, Sunil Lavadiya

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(2), P. e0311431 - e0311431

Published: Feb. 3, 2025

Cervical cancer belongs to the most dangerous types of cancers posing considerable threat women’s survival. It is often diagnosed in advanced stages as precancerous lesions are symptom-free and difficult identify. Microwave imaging, especially terahertz (THz) range, a convenient noninvasive detection tool. enables characterization biological tissues discrimination between healthy malignant ones. This study presents novel triple-band biosensor based on metamaterials (MTMs). By leveraging unique properties MTMs, proposed operates perfect absorber. exploits resonant modes THz spectrum achieve remarkable sensitivity. Meticulous selection sensor geometry dimensions efficient miniaturization. Meanwhile, utilization frequency-domain data detect refractive index changes improves resolution cancerous tissue identification. Extensive numerical investigations corroborate its ability carry out reliable early-stage cervical diagnosis. includes identification spatial extent tissue. Excellent electrical accompanied by compact size, which highly desirable for non-invasive portable applications.

Language: Английский

Citations

0
Enhanced Axial Resolution in Dermascopy using Broadband RGB Flat Lens DOI Creative Commons
Aqeel ur Rehman,

Ramna Khalid,

Isma Javed

et al.

Optical Materials Express, Journal Year: 2024, Volume and Issue: 14(11), P. 2623 - 2623

Published: Oct. 9, 2024

Dermoscopy is a diagnostic tool in biomedical science, enabling non-invasive, high-resolution imaging for early detection and diagnosis of skin diseases. Although there have been considerable improvements functionality applications dermoscopy, enhancement depth-of-focus (DOF) detailed multiple layers needs to be addressed. High axial length improves the function by providing more comprehensive understanding subsurface structures abnormalities. We proposed flat lens solution enhanced resolution that aids differentiating between benign malignant lesions, improving accuracy patient outcomes. This study presents an all-dielectric design metalens, which uses titanium dioxide (TiO 2 ) simultaneously achieve maximum transmission extended resolution. Our designed metalens are optimized broadband visible light regimes from 488 nm 633 nm, offering performance across this broad spectral range. Using (EDOF) has enabled healthcare experts substantially enhance dermoscopy. results ability scan dermis epidermis real time diagnosis. technology integration into medical engineering increases real-time diagnostics, improved dermoscopy examinations.

Language: Английский

Citations

0