The Brain’s Aging Resting State Functional Connectivity DOI Creative Commons
Ali Fahim Khan, Nada Saleh, Zachary A. Smith

et al.

Journal of Integrative Neuroscience, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 7, 2025

Resting state networks (RSNs) of the brain are characterized as correlated spontaneous time-varying fluctuations in absence goal-directed tasks. These can be local or large-scale spanning brain. The study spatiotemporal properties such has helped understand brain’s fundamental functional organization under healthy and diseased states. As we age, these change. Moreover, RSNs exhibit neural plasticity to compensate for loss cognitive functions. This narrative review aims summarize current knowledge from magnetic resonance imaging (fMRI) studies on age-related alterations RSNs. Underlying mechanisms influencing changes discussed. Methodological challenges future directions also addressed. By providing an overview this field, guide research endeavors aimed at promoting aging developing effective interventions impairment neurodegenerative diseases.

Language: Английский

The Brain’s Aging Resting State Functional Connectivity DOI Creative Commons
Ali Fahim Khan, Nada Saleh, Zachary A. Smith

et al.

Journal of Integrative Neuroscience, Journal Year: 2025, Volume and Issue: 24(1)

Published: Jan. 7, 2025

Resting state networks (RSNs) of the brain are characterized as correlated spontaneous time-varying fluctuations in absence goal-directed tasks. These can be local or large-scale spanning brain. The study spatiotemporal properties such has helped understand brain’s fundamental functional organization under healthy and diseased states. As we age, these change. Moreover, RSNs exhibit neural plasticity to compensate for loss cognitive functions. This narrative review aims summarize current knowledge from magnetic resonance imaging (fMRI) studies on age-related alterations RSNs. Underlying mechanisms influencing changes discussed. Methodological challenges future directions also addressed. By providing an overview this field, guide research endeavors aimed at promoting aging developing effective interventions impairment neurodegenerative diseases.

Language: Английский

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