Military Medical Research,
Journal Year:
2025,
Volume and Issue:
12(1)
Published: April 27, 2025
Abstract
Brain
diseases
are
characterized
by
high
incidence,
disability,
and
mortality
rates.
Their
elusive
nature
poses
a
significant
challenge
for
early
diagnosis.
Magnetic
particle
imaging
(MPI)
is
novel
technique
with
sensitivity,
temporal
resolution,
no
ionizing
radiation.
It
relies
on
the
nonlinear
magnetization
response
of
superparamagnetic
iron
oxide
nanoparticles
(SPIONs),
allowing
visualization
spatial
concentration
distribution
SPIONs
in
biological
tissues.
MPI
expected
to
become
mainstream
technology
diagnosis
brain
diseases,
such
as
cancerous,
cerebrovascular,
neurodegenerative,
inflammatory
diseases.
This
review
provides
an
overview
principles
MPI,
explores
its
potential
applications
discusses
prospects
management
these
IEEE Transactions on Medical Imaging,
Journal Year:
2023,
Volume and Issue:
42(12), P. 3524 - 3539
Published: June 28, 2023
Imputation
of
missing
images
via
source-to-target
modality
translation
can
improve
diversity
in
medical
imaging
protocols.
A
pervasive
approach
for
synthesizing
target
involves
one-shot
mapping
through
generative
adversarial
networks
(GAN).
Yet,
GAN
models
that
implicitly
characterize
the
image
distribution
suffer
from
limited
sample
fidelity.
Here,
we
propose
a
novel
method
based
on
diffusion
modeling,
SynDiff,
improved
performance
translation.
To
capture
direct
correlate
distribution,
SynDiff
leverages
conditional
process
progressively
maps
noise
and
source
onto
image.
For
fast
accurate
sampling
during
inference,
large
steps
are
taken
with
projections
reverse
direction.
enable
training
unpaired
datasets,
cycle-consistent
architecture
is
devised
coupled
diffusive
non-diffusive
modules
bilaterally
translate
between
two
modalities.
Extensive
assessments
reported
utility
against
competing
multi-contrast
MRI
MRI-CT
Our
demonstrations
indicate
offers
quantitatively
qualitatively
superior
baselines.
Visual Computing for Industry Biomedicine and Art,
Journal Year:
2022,
Volume and Issue:
5(1)
Published: Oct. 1, 2022
Abstract
Magnetic
particle
imaging
(MPI)
is
an
emerging
molecular
technique
with
high
sensitivity
and
temporal-spatial
resolution.
Image
reconstruction
important
research
topic
in
MPI,
which
converts
induced
voltage
signal
into
the
image
of
superparamagnetic
iron
oxide
particles
concentration
distribution.
MPI
primarily
involves
system
matrix-
x-space-based
methods.
In
this
review,
we
provide
a
detailed
overview
status
future
trends
these
two
addition,
review
application
deep
learning
methods
current
open
sources
MPI.
Finally,
opinions
on
are
presented.
We
hope
promotes
use
clinical
applications.
IEEE Transactions on Medical Imaging,
Journal Year:
2023,
Volume and Issue:
42(12), P. 3639 - 3650
Published: July 20, 2023
Magnetic
particle
imaging
(MPI)
is
an
emerging
technique
for
determining
magnetic
nanoparticle
distributions
in
biological
tissues.
Although
system-matrix
(SM)-based
image
reconstruction
offers
higher
quality
than
the
X-space-based
approach,
SM
calibration
measurement
time-consuming.
Additionally,
should
be
recalibrated
if
tracer's
characteristics
or
field
environment
change,
and
repeated
further
increase
required
labor
time.
Therefore,
fast
essential
MPI.
Existing
methods
commonly
treat
each
row
of
as
independent
others,
but
rows
are
inherently
related
through
coil
channel
frequency
index.
As
these
two
elements
can
regarded
additional
multimodal
information,
we
leverage
transformer
architecture
with
a
self-attention
mechanism
to
encode
them.
has
shown
superiority
fusion
learning
across
several
fields,
its
high
complexity
may
lead
overfitting
when
labeled
data
scarce.
Compared
(i.e.,
full
size),
low-resolution
easily
obtained,
fully
using
such
alleviate
overfitting.
Accordingly,
propose
pseudo-label-based
progressive
pretraining
strategy
unlabeled
data.
Our
method
outperforms
existing
on
public
real-world
OpenMPI
dataset
simulation
dataset.
Moreover,
our
improves
resolution
in-house
MPI
scanners
without
requiring
full-size
measurements.
Ablation
studies
confirm
contributions
modeling
inter-row
relations
proposed
strategy.
IEEE Transactions on Medical Imaging,
Journal Year:
2023,
Volume and Issue:
43(1), P. 321 - 334
Published: Aug. 1, 2023
Magnetic
particle
imaging
(MPI)
offers
unparalleled
contrast
and
resolution
for
tracing
magnetic
nanoparticles.
A
common
procedure
calibrates
a
system
matrix
(SM)
that
is
used
to
reconstruct
data
from
subsequent
scans.
The
ill-posed
reconstruction
problem
can
be
solved
by
simultaneously
enforcing
consistency
based
on
the
SM
regularizing
solution
an
image
prior.
Traditional
hand-crafted
priors
cannot
capture
complex
attributes
of
MPI
images,
whereas
recent
methods
learned
suffer
extensive
inference
times
or
limited
generalization
performance.
Here,
we
introduce
novel
physics-driven
method
deep
equilibrium
model
with
(DEQ-MPI).
DEQ-MPI
reconstructs
images
augmenting
neural
networks
into
iterative
optimization,
as
inspired
unrolling
in
learning.
Yet,
conventional
are
computationally
restricted
few
iterations
resulting
non-convergent
solutions,
they
use
measures
yield
suboptimal
distribution.
instead
trains
implicit
mapping
maximize
quality
convergent
solution,
it
incorporates
measure
better
account
Demonstrations
simulated
experimental
indicate
achieves
superior
competitive
time
state-of-the-art
methods.
IEEE Transactions on Medical Imaging,
Journal Year:
2023,
Volume and Issue:
42(6), P. 1859 - 1874
Published: Jan. 30, 2023
The
long
acquisition
time
has
limited
the
accessibility
of
magnetic
resonance
imaging
(MRI)
because
it
leads
to
patient
discomfort
and
motion
artifacts.
Although
several
MRI
techniques
have
been
proposed
reduce
time,
compressed
sensing
in
(CS-MRI)
enables
fast
without
compromising
SNR
resolution.
However,
existing
CS-MRI
methods
suffer
from
challenge
aliasing
This
results
noise-like
textures
missing
fine
details,
thus
leading
unsatisfactory
reconstruction
performance.
To
tackle
this
challenge,
we
propose
a
hierarchical
perception
adversarial
learning
framework
(HP-ALF).
HP-ALF
can
perceive
image
information
mechanism:
image-level
patch-level
perception.
former
visual
difference
entire
image,
achieve
artifact
removal.
latter
regions
recover
details.
Specifically,
achieves
mechanism
by
utilizing
multilevel
perspective
discrimination.
discrimination
provide
two
perspectives
(overall
regional)
for
learning.
It
also
utilizes
global
local
coherent
discriminator
structure
generator
during
training.
In
addition,
contains
context-aware
block
effectively
exploit
slice
between
individual
images
better
experiments
validated
on
three
datasets
demonstrate
effectiveness
its
superiority
comparative
methods.