Military Medical Research,
Journal Year:
2025,
Volume and Issue:
12(1)
Published: April 27, 2025
Abstract
Brain
diseases
are
characterized
by
high
incidence,
disability,
and
mortality
rates.
Their
elusive
nature
poses
a
significant
challenge
for
early
diagnosis.
Magnetic
particle
imaging
(MPI)
is
novel
technique
with
sensitivity,
temporal
resolution,
no
ionizing
radiation.
It
relies
on
the
nonlinear
magnetization
response
of
superparamagnetic
iron
oxide
nanoparticles
(SPIONs),
allowing
visualization
spatial
concentration
distribution
SPIONs
in
biological
tissues.
MPI
expected
to
become
mainstream
technology
diagnosis
brain
diseases,
such
as
cancerous,
cerebrovascular,
neurodegenerative,
inflammatory
diseases.
This
review
provides
an
overview
principles
MPI,
explores
its
potential
applications
discusses
prospects
management
these
Abstract
Recent
works
have
shown
that
Transformer's
excellent
performances
on
natural
language
processing
tasks
can
be
maintained
image
analysis
tasks.
However,
the
complicated
clinical
settings
in
medical
and
varied
disease
properties
bring
new
challenges
for
use
of
Transformer.
The
computer
vision
engineering
communities
devoted
significant
effort
to
research
based
Transformer
with
especial
focus
scenario‐specific
architectural
variations.
In
this
paper,
we
comprehensively
review
rapidly
developing
area
by
covering
latest
advances
Transformer‐based
methods
different
settings.
We
first
give
introduction
basic
mechanisms
including
implementations
selfattention
typical
architectures.
important
problems
various
data
modalities,
visual
tasks,
organs
diseases
are
then
reviewed
systemically.
carefully
collect
276
very
recent
76
public
datasets
an
organized
structure.
Finally,
discussions
open
future
directions
also
provided.
expect
up‐to‐date
roadmap
serve
as
a
reference
source
pursuit
boosting
development
field.
IEEE Transactions on Medical Imaging,
Journal Year:
2022,
Volume and Issue:
41(12), P. 3895 - 3906
Published: Aug. 15, 2022
Learning-based
translation
between
MRI
contrasts
involves
supervised
deep
models
trained
using
high-quality
source-
and
target-contrast
images
derived
from
fully-sampled
acquisitions,
which
might
be
difficult
to
collect
under
limitations
on
scan
costs
or
time.
To
facilitate
curation
of
training
sets,
here
we
introduce
the
first
semi-supervised
model
for
contrast
(ssGAN)
that
can
directly
undersampled
k-space
data.
enable
learning
data,
ssGAN
introduces
novel
multi-coil
losses
in
image,
k-space,
adversarial
domains.
The
are
selectively
enforced
acquired
samples
unlike
traditional
single-coil
synthesis
models.
Comprehensive
experiments
retrospectively
multi-contrast
brain
datasets
provided.
Our
results
demonstrate
yields
par
performance
a
model,
while
outperforming
coil-combined
magnitude
images.
It
also
outperforms
cascaded
reconstruction-synthesis
where
is
following
self-supervised
reconstruction
Thus,
holds
great
promise
improve
feasibility
learning-based
synthesis.
Physics in Medicine and Biology,
Journal Year:
2023,
Volume and Issue:
68(4), P. 045014 - 045014
Published: Jan. 23, 2023
Objective.
Magnetic
particle
imaging
(MPI)
is
a
novel
modality.
It
crucial
to
acquire
accurate
localization
of
the
superparamagnetic
iron
oxide
nanoparticles
distributions
in
MPI.
However,
spatial
resolution
unidirectional
Cartesian
trajectory
MPI
exhibits
anisotropy,
which
blurs
boundaries
images
and
makes
precise
difficult.
In
this
paper,
we
propose
an
anisotropic
edge-preserving
network
(AEP-net)
alleviate
MPI.Methods.
AEP-net
resolve
anisotropy
by
constructing
asymmertic
convolution.
To
recover
edge
information,
design
uncertainty
region
module.
addition,
evaluated
performance
proposed
model
using
simulations
experimental
data.Results.
The
results
show
that
alleviates
preserves
details
image.
By
comparing
visualization
metrics,
demonstrate
our
method
superior
other
methods.Significance.
produces
devices
promotes
quantization,
promote
biomedical
applications
IEEE Journal of Biomedical and Health Informatics,
Journal Year:
2023,
Volume and Issue:
28(3), P. 1273 - 1284
Published: Dec. 5, 2023
Monitoring
of
prevalent
airborne
diseases
such
as
COVID-19
characteristically
involves
respiratory
assessments.
While
auscultation
is
a
mainstream
method
for
preliminary
screening
disease
symptoms,
its
utility
hampered
by
the
need
dedicated
hospital
visits.
Remote
monitoring
based
on
recordings
sounds
portable
devices
promising
alternative,
which
can
assist
in
early
assessment
that
primarily
affects
lower
tract.
In
this
study,
we
introduce
novel
deep
learning
approach
to
distinguish
patients
with
from
healthy
controls
given
audio
cough
or
breathing
sounds.
The
proposed
leverages
hierarchical
spectrogram
transformer
(HST)
representations
HST
embodies
self-attention
mechanisms
over
local
windows
spectrograms,
and
window
size
progressively
grown
model
stages
capture
global
context.
compared
against
state-of-the-art
conventional
deep-learning
baselines.
Demonstrations
crowd-sourced
multi-national
datasets
indicate
outperforms
competing
methods,
achieving
90%
area
under
receiver
operating
characteristic
curve
(AUC)
detecting
cases.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(5), P. e26775 - e26775
Published: Feb. 28, 2024
Existing
approaches
to
3D
medical
image
segmentation
can
be
generally
categorized
into
convolution-based
or
transformer-based
methods.
While
convolutional
neural
networks
(CNNs)
demonstrate
proficiency
in
extracting
local
features,
they
encounter
challenges
capturing
global
representations.
In
contrast,
the
consecutive
self-attention
modules
present
vision
transformers
excel
at
long-range
dependencies
and
achieving
an
expanded
receptive
field.
this
paper,
we
propose
a
novel
approach,
termed
SCANeXt,
for
segmentation.
Our
method
combines
strengths
of
dual
attention
(Spatial
Channel
Attention)
ConvNeXt
enhance
representation
learning
images.
particular,
mechanism
crafted
encompass
spatial
channel
relationships
throughout
entire
feature
dimension.
To
further
extract
multiscale
introduce
depth-wise
convolution
block
inspired
by
after
block.
Extensive
evaluations
on
three
benchmark
datasets,
namely
Synapse,
BraTS,
ACDC,
effectiveness
our
proposed
terms
accuracy.
SCANeXt
model
achieves
state-of-the-art
result
with
Dice
Similarity
Score
95.18%
ACDC
dataset,
significantly
outperforming
current
IEEE Transactions on Medical Imaging,
Journal Year:
2024,
Volume and Issue:
43(8), P. 2949 - 2959
Published: April 1, 2024
Magnetic
particle
imaging
(MPI)
uses
nonlinear
response
signals
to
noninvasively
detect
magnetic
nanoparticles
in
space,
and
its
quantitative
properties
hold
promise
for
future
precise
treatments.
In
reconstruction,
the
system
matrix
based
method
necessitates
suitable
regularization
terms,
such
as
Tikhonov
or
non-negative
fused
lasso
(NFL)
regularization,
stabilize
solution.
While
NFL
offers
clearer
edge
information
than
it
carries
a
biased
estimate
of
l
1
penalty,
leading
an
underestimation
reconstructed
concentration
adversely
affecting
properties.
this
paper,
new
nonconvex
including
min-max
concave
(MC)
total
variation
(TV)
is
proposed.
This
utilized
MC
penalty
provide
nearly
unbiased
sparse
constraints
adds
TV
uniform
intensity
distribution
images.
By
combining
alternating
direction
multiplication
(ADMM)
two-step
parameter
selection
method,
more
accurate
MPI
reconstruction
was
realized.
The
performance
proposed
verified
on
simulation
data,
Open-MPI
dataset,
measured
data
from
homemade
scanner.
results
indicate
that
achieves
better
image
quality
while
maintaining
properties,
thus
overcoming
drawback
by
providing
information.
particular,
reduced
relative
error
28%
8%.
IEEE Transactions on Computational Imaging,
Journal Year:
2023,
Volume and Issue:
9, P. 289 - 297
Published: Jan. 1, 2023
The
frequency
component
compression
method
(FCCM)
has
been
widely
used
in
magnetic
particle
imaging
(MPI)
technology
to
improve
reconstruction
efficiency.
This
can
reduce
the
time
by
using
signal-to-noise
ratio
(SNR)
feature
remove
high
noise
components.
To
further
accelerate
reconstruction,
a
dual-feature
(DF-FCCM)
was
developed
herein.
A
new
energy
spectral
density
(ESD)
introduced
describe
level
of
measurement
signal.
By
SNR
and
ESD
feature,
DF-FCCM
select
valuable
components
that
contain
low
both
signal
system
matrix.
be
reduced
fewer
more
information.
efficiency
robustness
proposed
validated
through
extensive
simulation
experiments.
Further
real
experiments
based
on
OpenMPI
data
set
verified
applied
MPI
reconstruction.
Compared
previous
SNR-FCCM,
achieve
similar
or
better
quality
25%
time.
efficiently
potential
online
imaging,
which
is
essential
for
pre-clinical
clinical
applications.
IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing,
Journal Year:
2023,
Volume and Issue:
16, P. 4457 - 4468
Published: Jan. 1, 2023
Superresolution
(SR)
of
remote
sensing
images
aims
to
restore
high-quality
information
from
low-resolution
images.
Recently,
it
has
witnessed
great
strides
with
the
rapid
development
deep
learning
(DL)
techniques.
Despite
their
good
performance,
these
DL-based
models
are
often
ineffective
in
balancing
global
and
local
feature
extraction.
Moreover,
they
usually
hindered
by
poor
image
reconstruction
capability
decoder
inside
SR
models.
To
cope
this
problem,
work
proposes
a
novel
context-driven
residual
dense
network
(GCRDN)
for
satellite
based
on
encoder
architecture.
In
particular,
proposed
is
endowed
nonlocal
sparse
attention
modules
incorporated
into
learn
robust
representations
features.
Furthermore,
equipped
back-sampling
blocks
devised
fully
exploit
maps
extracted
encoder.
Extensive
experimental
comparisons
two
multisensor
datasets
confirm
that
GCRDN
achieves
impressive
performance
terms
perceptual
quality
fidelity.