Current Status of Prurigo Nodularis in Japan: A Retrospective Study Using a Health Insurance Claims Database DOI Open Access
Atsuyuki Igarashi, Takuo Yoshida,

Yoshinori Sunaga

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(6), P. 1872 - 1872

Published: March 11, 2025

Background/Objectives: Prurigo nodularis (PN) is associated with considerable disease burden. Limited information exists about the epidemiology, treatment patterns, and impact of PN. This retrospective study used Japanese health insurance claims data to investigate prevalence incidence PN from 2006 2021. Methods: A cross-sectional design was estimate longitudinally; a cohort assess comorbidities, healthcare resource utilization (HCRU). Results: Over period, 297,545 10,081,414 individuals were available annually; in 2020, 1946 diagnosed The showed little variation over period; 2021, 41 per 100,000 persons. Although there tendency for higher childhood, similar other age groups slightly females. Inflammatory skin diseases atopic diathesis common comorbidities. most prescribed treatments adults topical steroids (78%), oral antihistamines (68%), moisturizers (54%). Oral steroids, macrolides, psychotropics >10% patients. Individuals who also had dermatitis (AD) received cumulative doses stronger potency local steroid injections, than those without concomitant AD. Additionally, HCRU Conclusions: patients are usually treated according guidelines, an unmet need more effective due frequent use intensive late-line treatments.

Language: Английский

Current Status of Prurigo Nodularis in Japan: A Retrospective Study Using a Health Insurance Claims Database DOI Open Access
Atsuyuki Igarashi, Takuo Yoshida,

Yoshinori Sunaga

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(6), P. 1872 - 1872

Published: March 11, 2025

Background/Objectives: Prurigo nodularis (PN) is associated with considerable disease burden. Limited information exists about the epidemiology, treatment patterns, and impact of PN. This retrospective study used Japanese health insurance claims data to investigate prevalence incidence PN from 2006 2021. Methods: A cross-sectional design was estimate longitudinally; a cohort assess comorbidities, healthcare resource utilization (HCRU). Results: Over period, 297,545 10,081,414 individuals were available annually; in 2020, 1946 diagnosed The showed little variation over period; 2021, 41 per 100,000 persons. Although there tendency for higher childhood, similar other age groups slightly females. Inflammatory skin diseases atopic diathesis common comorbidities. most prescribed treatments adults topical steroids (78%), oral antihistamines (68%), moisturizers (54%). Oral steroids, macrolides, psychotropics >10% patients. Individuals who also had dermatitis (AD) received cumulative doses stronger potency local steroid injections, than those without concomitant AD. Additionally, HCRU Conclusions: patients are usually treated according guidelines, an unmet need more effective due frequent use intensive late-line treatments.

Language: Английский

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