Perception and Longevity Control in Invertebrate Model Organisms—A Mini-Review of Recent Advances

Biomolecules, Journal Year: 2025, Volume and Issue: 15(2), P. 187 - 187

Published: Jan. 28, 2025

Perception alone can, in some cases, be sufficient to modulate aging and longevity. These influences on are perhaps mediated by changes motivational states that regulate metabolism physiology impact health. Simple invertebrate models uniquely enable detailed dissection of integrative pathways linking perceptions remain the leading systems for advancing this field. Over past 25 years, studies using fruit fly Drosophila melanogaster nematode Caenorhabditis elegans have demonstrated sensory cues, such as those related food or mating, can influence independently physical acts associated with them. In review, we highlight recent advancements these models, focusing two key areas progress: (i) discovery lifespan modulation driven novel cues across multiple modalities, including non-sexual social experience, light, dietary choices; (ii) assignment new aging-regulation functions specific neurons downstream perception. The latter offers an exciting first glimpse at neuronal circuits integrating states, physiology, aging.

Language: Английский

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Neglected patterns of variation in transgenerational plasticity: The importance of different sources of environmental variation differs across ages and sexes in a cyprinid fish

Functional Ecology, Journal Year: 2024, Volume and Issue: 38(6), P. 1391 - 1406

Published: April 15, 2024

Abstract Adaptive transgenerational plasticity (TGP) requires individuals to integrate environmental experience across multiple sources. However, few empirical studies have considered that the relative relevance of certain sources might vary ontogeny and sexes. Here, we address this knowledge gap by studying inducible antipredator defences, one most convincing examples TGP. We assessed individual combined effects perceived high predation risk in mothers, fathers, caring males personal environments on morphology juvenile, adult male female cyprinids Pimephales promelas . Parental rather than determined morphological defence expression ages sexes, likely because parents had a longer sampling period. In juveniles males, egg‐mediated outweighed sperm‐mediated induction body shape differences, eggs can transmit information beyond epigenomes. females, where responses be interpreted as life‐history plasticity, from egg sperm were equally important, resulting different integration mechanisms between plasticity. The importance care‐mediated gamete‐mediated variation changed they represent short‐ long‐term experience, respectively. Instead, both again potentially owing lag‐times care intensity only contributed marginally formation. These results highlight age‐ sex‐specific prioritization experiences so generate optimal phenotypes. Read free Plain Language Summary for article Journal blog.

Language: Английский

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The combined effects of atrazine and warming on environmental adaptability in lizards (Eremias argus) from the perspective of a life-history traits trade-off: Gender differences in trade-off strategies may reverse mortality risk

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 879, P. 163078 - 163078

Published: March 25, 2023

Language: Английский

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Perception of dead conspecifics increases reproductive investment in fruit flies

Functional Ecology, Journal Year: 2022, Volume and Issue: 36(8), P. 1834 - 1844

Published: June 9, 2022

Abstract Adaptive plasticity in life‐history traits is often critical to maximize fitness the face of environmental heterogeneity. For example, many organisms respond a threat their survival (and hence residual reproductive value) by adaptively increasing investment into current reproduction (i.e. ‘terminal investment’). A key successful terminal use adequate cues extrinsic mortality sources. In species that live at high population densities, presence dead conspecifics could potentially act as reliable cue sources (e.g. via pathogens). We experimentally tested this idea using model organism Drosophila melanogaster , pest experiences marked demographic shifts. monitored output young mated females during repeated bouts egg laying exposed) or absence controls) conspecifics, interspersed mating periods where were always absent. Dead‐exposed produced more offspring than controls when but fewer subsequently removed periods). These changes repeatable across time, and are thus indicative behaviour induced perception conspecifics. Flies responded equally starvation‐induced flash‐frozen indicating cause death irrelevant trigger plastic response observed, per se. Finally, we found dead‐exposed heavier daughters (but not sons) (when absent). species, body size correlates strongly with female (than male) fitness, so higher daughter weight congruent investment. Altogether, these results show leads highly adjustments form increased both quantity quality offspring. discuss context other alternative hypotheses. Read free Plain Language Summary for article on Journal blog.

Language: Английский

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Sex‐specific paternal age effects on offspring quality in Drosophila melanogaster

Journal of Evolutionary Biology, Journal Year: 2023, Volume and Issue: 36(4), P. 720 - 729

Published: March 22, 2023

Abstract Advanced paternal age has been repeatedly shown to modulate offspring quality via male‐ and/or female‐driven processes, and there are theoretical reasons expect that some of these effects can be sex‐specific. For example, sex allocation theory predicts that, when mated with low‐condition males, mothers should invest more in their daughters compared sons. This is because male fitness generally condition‐dependent variable than female fitness, which makes it less risky offspring. Here, we explore whether affect the quantity a sex‐specific way using Drosophila melanogaster as model organism. In order understand contribution male‐driven processes on effects, also measured seminal vesicle size young older males explored its relationship reproductive success quality. Older had lower competitive success, expected, but was no difference between ratio males. However, found caused an increase (i.e., weight), this marked We discuss different may explain such effects.

Language: Английский

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Effects of spontaneous mutations on survival and reproduction of Drosophila serrata infected with Drosophila C virus

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: April 6, 2024

Abstract The impact of selection on host immune function genes has been widely documented. However, it remains essentially unknown how mutation influences the quantitative traits that acts on. Applying a classical accumulation (MA) experimental design in Drosophila serrata , we found mutational variation susceptibility (median time death, LT50) to C virus (DCV) was similar magnitude reported for intrinsic survival traits. mean LT50 did not change as mutations accumulated, suggestion no directional bias effects. Maintenance genetic variance is hypothesised be influenced by pleiotropic effects immunity and other contribute fitness. To investigate this, assayed female reproductive output subset MA lines with relatively long or short times under DCV infection. Longer tended associated lower output, suggesting affecting had investment Further studies are needed uncover general patterns effect responses fitness traits, determine might typically act new via their direct

Language: Английский

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Effects of spontaneous mutations on survival and reproduction of Drosophila serrata infected with Drosophila C virus

Evolution, Journal Year: 2024, Volume and Issue: 78(10), P. 1661 - 1672

Published: June 27, 2024

The impact of selection on host immune function genes has been widely documented. However, it remains essentially unknown how mutation influences the quantitative traits that acts on. Applying a classical accumulation (MA) experimental design in Drosophila serrata, we found mutational variation susceptibility (median time death, LT50) to C virus (DCV) was similar magnitude reported for intrinsic survival traits. Mean LT50 did not change as mutations accumulated, suggesting no directional bias effects. Maintenance genetic variance is hypothesized be influenced by pleiotropic effects immunity and other contribute fitness. To investigate this, assayed female reproductive output subset MA lines with relatively long or short times under DCV infection. Longer tended associated lower output, affecting had investment Further studies are needed uncover general patterns effect responses fitness traits, determine might typically act new via their direct

Language: Английский

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Reduced Survival Expectancy Weakens Reproductive Isolation Between Annual FishesGarcialebias reichertiandG. charrua

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Dec. 8, 2023

ABSTRACT Hybridization depends on reproductive isolation, which can be impacted by mate choice. Mate choice may vary temporally, as it is modulated several factors, including survival expectancy and future opportunities for reproduction. Garcialebias reicherti G. charrua are annual fishes with parapatric distributions that hybridize in the overlapping area of their distributions. They inhabit temporary ponds flood during autumn dry out spring, resulting decreased reproduction breeding season. We predicted a decrease would promote reduce isolation between G . By simulating desiccation early late season, we investigated effects risk phase season effort these species. As expected, our findings reveal influences both , effort. Notably, species under high Additionally, observed an increase frequency mating courtship events aggressive behaviours Our study suggests change rapidly within short period time, emphasizing influence temporal dynamics hybridization.

Language: Английский

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