Safety Evaluation of Fermented and Nonfermented Moringa oleifera Seeds in Healthy Albino Rats: Biochemical, Haematological, and Histological Studies DOI Creative Commons
Foluso Olutope Adetuyi, Emmanuel Sina Akintimehin, Kayode Olayele Karigidi

et al.

International Journal of Food Science, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Fermentation preserves and enhances food properties, but consuming locally fermented foods can cause health issues like flatulence, gastrointestinal disorders, kidney stones, sometimes death. This study evaluated the biochemical, haematological, histological effects of supplementing diets with Moringa oleifera seed (FMS) nonfermented (NFMS) in healthy albino rats. Male rats were fed containing 10%, 20%, 30% FMS NFMS for 14 days. No significant changes observed body weight or organ/body ratios. However, platelet count increased significantly (p < 0.05) at higher supplementation levels, suggesting enhanced haemostatic activity. While haematological parameters remained stable, 20% urea creatinine indicating potential renal stress. Histological analysis showed mild alterations more pronounced NFMS-fed mitigated antinutrient effects, enhancing safety. are safe up to inclusion, applications human nutrition functional development.

Language: Английский

The novel MAT1-1-2 gene of Golden-flower fungus from Fuzhuan Brick Tea is required for normal colony morphology and sexual development, and affects metabolism DOI
Jie Wang, Rui Zhang,

Z. Fei

et al.

Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106283 - 106283

Published: March 1, 2025

Language: Английский

Citations

0
Safety Evaluation of Fermented and Nonfermented Moringa oleifera Seeds in Healthy Albino Rats: Biochemical, Haematological, and Histological Studies DOI Creative Commons
Foluso Olutope Adetuyi, Emmanuel Sina Akintimehin, Kayode Olayele Karigidi

et al.

International Journal of Food Science, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Fermentation preserves and enhances food properties, but consuming locally fermented foods can cause health issues like flatulence, gastrointestinal disorders, kidney stones, sometimes death. This study evaluated the biochemical, haematological, histological effects of supplementing diets with Moringa oleifera seed (FMS) nonfermented (NFMS) in healthy albino rats. Male rats were fed containing 10%, 20%, 30% FMS NFMS for 14 days. No significant changes observed body weight or organ/body ratios. However, platelet count increased significantly (p < 0.05) at higher supplementation levels, suggesting enhanced haemostatic activity. While haematological parameters remained stable, 20% urea creatinine indicating potential renal stress. Histological analysis showed mild alterations more pronounced NFMS-fed mitigated antinutrient effects, enhancing safety. are safe up to inclusion, applications human nutrition functional development.

Language: Английский

Citations

0