Genome‐wide scans for signatures of selection in North African sheep reveals differentially selected regions between fat‐ and thin‐tailed breeds DOI
Slim Ben Jemaa,

Ghazi Yahyaoui,

Samia Kdidi

et al.

Animal Genetics, Journal Year: 2024, Volume and Issue: 56(1)

Published: Nov. 21, 2024

Abstract North Africa counts several sheep breeds that can be categorized as fat‐ and thin‐tailed. The former are well adapted to dryland environments. In this study, we used 50K genome‐wide single nucleotide polymorphism profiles from 462 animals representing nine fat‐tailed 13 thin‐tailed across localize genomic regions putatively under differential selective pressures between the two types of breeds. We observed genetic clines east west north south. east–west cline separates breeds, with exception Algerian Barbarine, which is closely related a genetically homogeneous cluster Moroccan Using combination three extended haplotype homozygosity tests, detected seven candidate divergent selection sheep. strongest signals reside on chromosomes 1 13, latter spanning BMP2 gene, known associated fat‐tail phenotype. Overall, in overlap genes adaptation desert‐like environments including adipogenesis, heat drought tolerance. Our results confirm previously reported target but also reveal novel specifically African populations.

Language: Английский

Genome‐wide scans for signatures of selection in North African sheep reveals differentially selected regions between fat‐ and thin‐tailed breeds DOI
Slim Ben Jemaa,

Ghazi Yahyaoui,

Samia Kdidi

et al.

Animal Genetics, Journal Year: 2024, Volume and Issue: 56(1)

Published: Nov. 21, 2024

Abstract North Africa counts several sheep breeds that can be categorized as fat‐ and thin‐tailed. The former are well adapted to dryland environments. In this study, we used 50K genome‐wide single nucleotide polymorphism profiles from 462 animals representing nine fat‐tailed 13 thin‐tailed across localize genomic regions putatively under differential selective pressures between the two types of breeds. We observed genetic clines east west north south. east–west cline separates breeds, with exception Algerian Barbarine, which is closely related a genetically homogeneous cluster Moroccan Using combination three extended haplotype homozygosity tests, detected seven candidate divergent selection sheep. strongest signals reside on chromosomes 1 13, latter spanning BMP2 gene, known associated fat‐tail phenotype. Overall, in overlap genes adaptation desert‐like environments including adipogenesis, heat drought tolerance. Our results confirm previously reported target but also reveal novel specifically African populations.

Language: Английский

Citations

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