Comparative safety of oral Janus kinase inhibitors and dupilumab in patients with atopic dermatitis: a population-based cohort study

Journal of Allergy and Clinical Immunology, Journal Year: 2024, Volume and Issue: 154(5), P. 1195 - 1203.e3

Published: Aug. 7, 2024

Language: Английский

Risk of infantile atopic dermatitis in neonatal lupus erythematosus: a retrospective cohort study

Frontiers in Immunology, Journal Year: 2025, Volume and Issue: 16

Published: March 27, 2025

Objectives The onset and progression of atopic dermatitis (AD) are closely linked to autoimmune status. While AD has been observed in children with neonatal lupus erythematosus (NLE), its relationship perinatal factors remains unclear. This study aimed identify early-life risk for the development NLE within their first two years life. Methods We conducted a multicenter, retrospective cohort using electronic medical records follow-up data from patients cohort. Children were categorized into non-AD groups based on whether they developed by age two. Univariate multivariate analyses performed compare general clinical between groups. Results incidence was 27.27 (21/77). Compared group, group had significantly lower use oral probiotics intravenous gamma globulin, but higher rates small-for-gestational-age (SGA) status, hypocomplementemia, thrombocytopenia, anti-SSA, anti-SSB, double antibody (anti-SSA, anti-SSB) positivity, antibiotic use, systemic glucocorticoid (GC) treatment. Logistic regression analysis revealed that protective factor against AD, while positivity GC factors. Conclusion In NLE, associated reduced administration increased However, limited sample size this warrants further findings.

Language: Английский

Allergic rhinitis and keratoconus: a systematic review and meta-analysis

The Journal of Allergy and Clinical Immunology In Practice, Journal Year: 2024, Volume and Issue: 12(11), P. 3096 - 3104

Published: June 6, 2024

Language: Английский