Global prevalence of mild cognitive impairment among older adults living in nursing homes: a meta-analysis and systematic review of epidemiological surveys

Translational Psychiatry, Journal Year: 2023, Volume and Issue: 13(1)

Published: March 11, 2023

Abstract Mild cognitive impairment (MCI) is the early stage of between expected decline normal aging and more serious dementia. This meta-analysis systematic review explored pooled global prevalence MCI among older adults living in nursing homes its relevant factors. The protocol was registered INPLASY (INPLASY202250098). PubMed, Web Science, Embase, PsycINFO, CINAHL databases were systematically searched from their respective inception dates to 8 January 2022. inclusion criteria made based on PICOS acronym, as follows: Participants ( P ): Older homes; Intervention I not applicable; Comparison C Outcome O or data can generate according study-defined criteria; Study design (S): cohort studies (only baseline extracted) cross-sectional with accessible published a peer-reviewed journal. Studies involving mixed resources, reviews, meta-analyses, case studies, commentaries excluded. Data analyses performed using Stata Version 15.0. Random effects model used synthesize overall MCI. An 8-item instrument for epidemiological assess quality included studies. A total 53 articles 376,039 participants mean age ranging 64.42 86.90 years 17 countries. 21.2% (95% CI: 18.7–23.6%). Subgroup meta-regression revealed that screening tools significantly associated prevalence. Montreal Cognitive Assessment (49.8%) had higher than those other instruments. No significant publication bias found. Several limitations warrant attention this study; example, heterogeneity remained some factors examined due insufficient data. Adequate measures allocation resources are needed address high homes.

Language: Английский

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Suicidality in clinically stable bipolar disorder and schizophrenia patients during the COVID-19 pandemic

Translational Psychiatry, Journal Year: 2022, Volume and Issue: 12(1)

Published: July 29, 2022

Abstract The coronavirus disease 2019 (COVID-19) pandemic has a disproportionate impact on vulnerable subpopulations, including those with severe mental illness (SMI). This study examined the one-year prevalence of suicidal ideation (SI), suicide plans (SP), and attempts (SA) in bipolar disorder (BD) schizophrenia (SCZ) patients during pandemic. Prevalence rates were compared between two disorders associated factors examined. A survey was conducted six tertiary psychiatric hospitals units. People diagnosis BD or SCZ invited to participate. SI, SP, SA (suicidality for short) assessed using binary logistical regression. 1-year SP 58.3%, (95% CI: 54.1–62.6%), 38.4% 34.3–42.6%) 38.6% 34.5–42.8%), respectively, which higher than corresponding figures (SI: 33.2%, 95% 28.6–37.8%; SP: 16.8%, 13.2–20.5%; SA: 19.4%, 15.5–23.3%). Patients younger age, experience cyberbullying, history among family friends, fatigue physical pain score, inpatient status, depressive symptoms more likely have suicidality. COVID-19 increased risk suicidality, particularly patients. It is importance regularly screen suicidality even if they are clinically stable.

Language: Английский

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Study on correlations of BDNF, PI3K, AKT and CREB levels with depressive emotion and impulsive behaviors in drug-naïve patients with first-episode schizophrenia

BMC Psychiatry, Journal Year: 2023, Volume and Issue: 23(1)

Published: April 3, 2023

Abstract Background The pathogenesis of schizophrenia is still unknown. Nearly a half schizophrenic patients have depressive symptoms and even some impulsive behaviors. definite diagnosis an immense challenge. Molecular biology plays essential role in the research on schizophrenia. Objective This study aims to analyze correlations serum protein factor levels with emotion behaviors drug-naïve first-episode Methods Seventy sixty-nine healthy volunteers from health check center same period participated this study. In both patient group control group, brain-derived neurotrophic (BDNF), phosphatidylin-ositol-3-kinase (PI3K), kinase B (AKT), cAMP-response element binding (CREB) peripheral blood were tested by enzyme-linked immunosorbent assay (ELISA). evaluated Chinese versions Calgary Depression Scale for Schizophrenia (CDSS) Short UPPS-P Impulsive Behavior (S-UPPS-P), respectively. Results BDNF, PI3K, CREB lower than those while AKT level, total CDSS score S-UPPS-P all higher. score, correlated negatively but positively lack-of-premeditation (PR) sub-scale was not significantly AKT, levels. Conclusion Our results showed that different group. these factors are promising biomarkers predict depression

Language: Английский

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Association analysis of suicide risk assessed with Mini International Neuropsychiatric Interviews’ Suicidality Module in adolescents with non suicidal self injury disorder

Frontiers in Psychiatry, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 10, 2025

Objective Many adolescents with non suicidal self injury disorder have ideation. However, the specific characteristics of NSSI-D that contribute to high suicide risk remain unclear. This study observes association between depressive and anxiety symptoms among disorder, explores mechanism underlying in this population. Method Adolescents their parents from a psychiatric outpatient clinic were selected conduct paper questionnaires measure sociodemographic conditions. The Mini International Neuropsychiatric Interviews’ Suicidality Module(MINISM) was used assess participants. Self-Rating Depression Scale(SDS), Anxiety Scale(SAS), Piers-Harris Children’s Self-Concept Scale(PHCSS) symptoms, self-concept disorder. According cutoff value MINISM, sample divided into group non-high group. We performed descriptive correlation statistical network analysis types associated adolescents. Results A total 112 adolescent participants included study. Severe symptoms(OR=8.205, 95%CI=3.454-19.490) severe symptoms(OR=3.926, 95%CI=1.613-9.554) are suicide. father’s college/university education(p<0.01) is low self-concept(p<0.01) symptoms. Network suggests centrality education level. Conclusion results suggest related (based on MINISM) significantly, Interventions targeting may help reduce risk.

Language: Английский

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Using daily diary data to examine the period prior to a suicide attempt: an observational single-case study

Psychiatry Research Case Reports, Journal Year: 2025, Volume and Issue: unknown, P. 100251 - 100251

Published: Feb. 1, 2025

Language: Английский

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Sociodemographic, Clinical and Genetic Correlates of Aggressive and Auto-Aggressive Behaviour in Alcohol-Dependent Individuals – Preliminary Study

Psychology Research and Behavior Management, Journal Year: 2025, Volume and Issue: Volume 18, P. 55 - 66

Published: Jan. 1, 2025

Purpose: Reducing the risk of aggressive behaviour requires preventive measures that depend on our knowledge predisposing factors.The study's aim was to compare sociodemographic variables, clinical variables and frequency gene polymorphisms destructive between subpopulations individuals with a history suicidality and/or aggression, both being treated for alcohol dependence.Patients Methods: Sixty-nine patients hospitalised dependence participated in study.The sociodemographic, (SADD, BPAQ) genetic were compared alcohol-dependent selected according type behaviour, including suicidal control nonalcohol-dependent group.Polymorphisms MAOA, COMT, DRD2 DAT1 loci are known as factors mental dysfunctions investigated. Results:The subpopulation suicide attempts had longer time education than (11.9 vs 9.7 years).Patients aggression lower levels comorbid concomitant aggression.For MAOA G/G genotype tendency statistical significance observed among burdened by comparison significantly higher A/G cases controls.In case COMT polymorphism, reported less often group).Conclusion: Compared either only tendencies or those characterised poorer social performance.Genetic variation may be factor impulsive like especially aggression.

Language: Английский

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Factors associated with psychiatric consultation history and methods of suicide in individuals who died by suicide in Osaka City: A retrospective study

Psychiatry and Clinical Neurosciences Reports, Journal Year: 2025, Volume and Issue: 4(2)

Published: April 7, 2025

Abstract Aim This retrospective study investigated the relationship among psychiatric consultation history, method of suicide, and background information individuals who died by based on postmortem obtained from Osaka Prefectural Medical Examiner's Office. Methods We analyzed data 343 cases suicide that occurred in City 2017, focusing factors associated with a history consultations. The Cochran–Armitage trend test was used to evaluate whether there significant linear distribution case counts across 10‐year age groups. Univariate multivariate logistic regression analyses were identify consultations prior death. Results results revealed female sex, attempts, choosing jumping as compared hanging Factors not having death being employed (compared unemployed), student older younger). no counts. Conclusion highlights need for targeted mental health interventions specific demographic groups, well further research impact conditions age‐related methods. These may contribute deeper understanding risk help improving prevention strategies.

Language: Английский

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The impact of suicide prevention training for nursing assistant students: Knowledge and willingness to intervene

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(5), P. e0323169 - e0323169

Published: May 7, 2025

Nursing assistants frequently encounter individuals at risk of suicidal behavior in various healthcare settings. This study aims to assess the impact suicide prevention training materials on nursing assistant students’ knowledge of, and willingness intervene behavior. Pre- post-training assessments were conducted using Revised Facts Suicide Quiz Willingness Intervene against Questionnaire measuring Repeated measures analyses used changes before after use teaching materials. Students significantly improved overall scores (from a pretest mean 9.55 ± 2.97 posttest 13.28 2.51, (p < .001) 85.63 8.22 92.28 8.93, .001.). Attitudes not significant predictor intention intervene. These findings underscore importance as means early intervention Fostering proactive attitude is crucial for identification cases within Finally, results targeted curricula social health-related vocational programs.

Language: Английский

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Deconvolution-based transcriptomic analysis in the hippocampus reveals cell type-specific risk genes and pathways associated with depression and suicide

Biological Psychiatry Global Open Science, Journal Year: 2025, Volume and Issue: unknown, P. 100530 - 100530

Published: May 1, 2025

Language: Английский

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Forensic analysis of suicide deaths: Comparing forensic information with public information and investigating factors contributing to psychiatric consultations

Psychiatry and Clinical Neurosciences Reports, Journal Year: 2024, Volume and Issue: 3(2)

Published: April 24, 2024

Abstract Aim This study aimed to examine the usefulness of forensic information on suicide deaths in Japan for epidemiological studies and determine factors that lead people with suicidal ideation seek psychiatric care prior attempting suicide. Methods We focused 514 occurred Osaka City 2019. First, whether data used this can be generalized these cases, we compared officially published by study, utilizing Pearson's χ 2 test. Next, were analyzed using multivariate logistic regression analysis confirm relationship between demographic likelihood having a history consultation before Results Both official showed higher number males than females who died suicide, no significant differences values sets. Multivariate correlations. More associated seeking consultation. However, those regular jobs or students more likely avoid Conclusion The findings provide insights into phenomenon perspective. results suggest may effective reducing Forensic should incorporated formulation suicide‐prevention policies conduct multifaceted improve measures.

Language: Английский

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