MICROBIOTA IN GASTROINTESTINAL MALIGNANCIES DOI

Ludovica Bricca,

Serena Porcari, Edoardo Savarino

et al.

Best Practice & Research Clinical Gastroenterology, Journal Year: 2024, Volume and Issue: 72, P. 101953 - 101953

Published: Sept. 1, 2024

Language: Английский

Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease DOI
Rafael Valdés‐Mas, Avner Leshem,

Danping Zheng

et al.

Cell, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

Citations

4

Probiotics for inflammatory bowel disease: Is there sufficient evidence? DOI Creative Commons

Yueying Ma,

Dandan Yang, Jin Huang

et al.

Open Life Sciences, Journal Year: 2024, Volume and Issue: 19(1)

Published: Jan. 1, 2024

Abstract Inflammatory bowel disease (IBD) refers to chronic inflammatory disorders of the gut. Ulcerative colitis (UC) and Crohn’s (CD) are two subtypes IBD. Evidence suggests that intestinal microbiota plays a role in pathogenesis IBD, so probiotics have garnered lot interest as potential treatment or prevention for However, clinical evidence efficacy is still debatable. We performed literature review. An advanced search considered studies on probiotic IBD from inception 2023 PubMed, Embase, Cochrane Library, Web Science. In UC with probiotics, only Escherichia coli Nissle 1917 maintenance remission, Bifidobacterium VSL#3 induction remission patients mild moderately active shown strong evidence. Currently, there no definitive conclusions regarding effectiveness CD. The mechanism may be related reducing oxidative stress, repairing barrier, regulating flora balance, modulating immune response. Differences benefits between CD attributable different lesion extent immune-mediated pathophysiology. More robust randomized trials required validate safety diverse strains

Language: Английский

Citations

10

Gut microbiota and healthy longevity DOI
Jia Luo, Shan Liang, Feng Jin

et al.

Science China Life Sciences, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 2, 2024

Language: Английский

Citations

6

Interaction between diet and genetics in patients with inflammatory bowel disease DOI Creative Commons
Daniéla Oliveira Magro, Lígia Yukie Sassaki, Júlio Maria Fonseca Chebli

et al.

World Journal of Gastroenterology, Journal Year: 2024, Volume and Issue: 30(12), P. 1644 - 1650

Published: March 28, 2024

In this editorial, we comment on the article by Marangoni et al , published in recent issue of World Journal Gastroenterology 2023; 29: 5618-5629, about “Diet as an epigenetic factor inflammatory bowel disease”. The authors emphasized role diet, especially interaction with genetics, promoting process disease (IBD) patients, focusing DNA methylation, histone modifications, and influence microRNAs. explore between gut microbiota, only way. Furthermore, provided dietary recommendations for patients IBD. Western characterized a low fiber content deficiency micronutrients, impacts short-chain fatty acids production may be related to pathogenesis On other hand, consumption Mediterranean diet fibers are associated reduced risk IBD flares, particularly Crohn’s (CD) patients. According guidance from International Organization Study Inflammatory Bowel Diseases (IOIBD), regular fruits vegetables while reducing saturated, trans, dairy fat, additives, processed foods rich maltodextrins, artificial sweeteners containing sucralose or saccharine is recommended CD For ulcerative colitis, IOIBD recommends increased intake natural sources omega-3 follows same restrictive aimed at possible inclusion red meats. conclusion, complex heterogeneous disease, future studies needed elucidate epigenetics microbiota

Language: Английский

Citations

3

In vitro digestion and fecal fermentation behaviors of exopolysaccharide from Morchella esculenta and its impacts on hypoglycemic activity via PI3K/Akt signaling and gut microbiota modulation DOI Creative Commons
Weihong Guo, Xuerui Wang, Biao Wang

et al.

Food Chemistry X, Journal Year: 2024, Volume and Issue: 24, P. 101870 - 101870

Published: Oct. 2, 2024

This study aimed to evaluate the effects of gastrointestinal digestion on physicochemical properties and hypoglycemic activity extracellular polysaccharides from

Language: Английский

Citations

3

Genetic insights into the gut microbiota, herpes zoster, and postherpetic neuralgia: a bidirectional two-sample Mendelian randomization study DOI Creative Commons

Zhimin Deng,

Yali Liu, Haiying Wang

et al.

Frontiers in Genetics, Journal Year: 2024, Volume and Issue: 15

Published: May 23, 2024

An increasing amount of evidence suggests that gastrointestinal diseases are risk factors for herpes zoster (HZ) and postherpetic neuralgia (PHN). Among them, the gut microbiota may play a crucial role in this process. Therefore, study aims to explore potential causal association between HZ PHN.

Language: Английский

Citations

2

Sinensetin from citrus peel alleviates DSS-induced inflammation by regulating gut microbiota and serum metabolism in mice DOI
Zuomin Hu,

Zhongxing Chu,

Xuke Ling

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: 62, P. 105066 - 105066

Published: Sept. 6, 2024

Language: Английский

Citations

2

Letter: The multifaceted role of Escherichia coli in influencing disorders of industrial populations DOI Creative Commons
Maria Rosa Ingrosso, Antonio Gasbarrini, Giovanni Cammarota

et al.

Alimentary Pharmacology & Therapeutics, Journal Year: 2024, Volume and Issue: 59(5), P. 717 - 718

Published: Feb. 13, 2024

LINKED CONTENT This article is linked to Faqerah et al papers. To view these articles, visit https://doi.org/10.1111/apt.17720 and https://doi.org/10.1111/apt.17883

Language: Английский

Citations

1

Letter: Diet‐microbiome interactions in inflammatory bowel disease—Navigating towards individualised dietary strategies DOI Open Access
Iris Barth, Corien L. Stevens, Colette J. Strokap

et al.

Alimentary Pharmacology & Therapeutics, Journal Year: 2024, Volume and Issue: 59(9), P. 1154 - 1155

Published: April 9, 2024

LINKED CONTENT This article is linked to Faqerah et al paper. To view this article, visit https://doi.org/10.1111/apt.17720

Language: Английский

Citations

1

Mouse diet and vendor impact microbiome perturbation and recovery from early-life pulses of amoxicillin DOI Creative Commons
Noelle Curtis-Joseph,

Rachel Ranitha Peterson,

Claire Brown

et al.

Frontiers in Microbiomes, Journal Year: 2024, Volume and Issue: 3

Published: July 29, 2024

The gut microbiome is a dynamic ecosystem shaped by various factors, including diet, sex, and environment. This system plays crucial role in host health, such that perturbation the form of antibiotics can lead to vast array negative outcomes. Accordingly, growing body work seeks develop interventions protect during antibiotic exposure. While it well established disrupt short term, how impact modulated factors as environment poorly understood. In this study, we analyzed diet early life (vendor origin) modulate recovery mice treated with oral amoxicillin. Utilizing 16S rRNA gene sequencing bioinformatic analyses, looked at response under high-sugar high-fat (Western) standard high-fiber mouse (Chow) diets male female C57BL/6 from Jackson Laboratory, Charles River Laboratories. composition each set had distinct pre-antibiotic starting point, depending on vendor, diet. These differences were further exacerbated exposure revealed group responded differently perturbation. particular, found Western an greater changes alpha, beta diversity, microbial when compared antibiotic-treated Chow cohort. detected blooms Enterobacteriaceae , Streptococcaceae Peptostreptococcaceae not also appeared be vendor sex dependent. less Bifidobacteriaceae Clostridia_UCG.014 Clostridiaceae Laboratory females while more Bacteroides Bilophila Parasutterella mice. narrow sense, these findings underscore importance considering source, examining antibiotics’ broader implications suggest will likely need utilize patient-specific microbiome-informed approaches development human therapeutics safeguard

Language: Английский

Citations

1