Rare and severe adverse events in children with inflammatory bowel disease DOI
Jiangwei Sun, Henrik Arnell, Jonas F. Ludvigsson

et al.

The Lancet Child & Adolescent Health, Journal Year: 2024, Volume and Issue: 8(9), P. e8 - e8

Published: Aug. 12, 2024

Language: Английский

Effects of microbial fermentation on the anti-inflammatory activity of Chinese yam polysaccharides DOI Creative Commons

Jinchu Yang,

Yi Zheng,

Yongfeng Yang

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 11

Published: Jan. 6, 2025

In this study, Chinese yam polysaccharides (CYPs) were fermented using Lactobacillus plantarum M616, and changes in the chemical composition, structure, anti-inflammatory activity of CYPs before after fermentation investigated. The carbohydrate content L. M616-fermented CYP (CYP-LP) increased from 71.03% ± 2.75 to 76.28% 2.37%, whereas protein polyphenol almost unaffected compared with those unfermented (CYP-NF). monosaccharide composition CYP-NF included rhamnose, arabinose, galactose, glucose, mannose a molar ratio 0.493:0.6695:0.9738:0.7655:12.4365. CYP-LP had same monosaccharides as CYP-NF, but was 0.3237:0.3457:0.8278:2.5541:10.4995. Meanwhile, molecular weight polydispersity CYP-LP, respectively, 124.774 kDa 6.58 (CYP-NF) 376.628 17.928, indicating low homogeneity. vitro antioxidant analysis showed that M616 varying effects on against DPPH, ABTS, hydroxyl, superoxide radicals. However, superior is more effective regulating dismutase, catalase, glutathione peroxidase, malondialdehyde, nitric oxide, tumor necrosis factor-α, interleukin-1β, interleukin-6 release lipopolysaccharide-induced RAW 264.7 macrophages. This study suggested potential ingredient drugs functional food.

Language: Английский

Citations

3
Treatment of inflammatory bowel disease with steroid‐sparing medications is age‐dependent – Results from a Danish nationwide cohort study, 2000–2018 DOI Creative Commons
Rie Louise Møller Nordestgaard, Mads Damsgaard Wewer, Mikkel Malham

et al.

Alimentary Pharmacology & Therapeutics, Journal Year: 2024, Volume and Issue: 60(4), P. 457 - 468

Published: June 10, 2024

Paediatric-onset and elderly-onset inflammatory bowel disease (IBD) present unique treatment challenges.

Language: Английский

Citations

5
Editorial: Mortality in immune‐mediated inflammatory diseases during early adulthood DOI
Paul Henderson

Alimentary Pharmacology & Therapeutics, Journal Year: 2024, Volume and Issue: 59(12), P. 1624 - 1625

Published: April 21, 2024

LINKED CONTENT This article is linked to Malham et al papers. To view these articles, visit https://doi.org/10.1111/apt.17994 and https://doi.org/10.1111/apt.18026 .

Language: Английский

Citations

1
Editorial: Mortality in immune‐mediated inflammatory diseases during early adulthood—Authors' reply DOI
Mikkel Malham, Sabine Jansson, Helene Ingels

et al.

Alimentary Pharmacology & Therapeutics, Journal Year: 2024, Volume and Issue: 59(12), P. 1626 - 1627

Published: May 6, 2024

LINKED CONTENT This article is linked to Malham et al papers. To view these articles, visit https://doi.org/10.1111/apt.17994 and https://doi.org/10.1111/apt.18012 .

Language: Английский

Citations

0
Rare and severe adverse events in children with inflammatory bowel disease - Authors' reply DOI
R Klomberg, Nicholas M. Croft, Lissy de Ridder

et al.

The Lancet Child & Adolescent Health, Journal Year: 2024, Volume and Issue: 8(9), P. e9 - e10

Published: Aug. 12, 2024

Language: Английский

Citations

0
Rare and severe adverse events in children with inflammatory bowel disease DOI
Jiangwei Sun, Henrik Arnell, Jonas F. Ludvigsson

et al.

The Lancet Child & Adolescent Health, Journal Year: 2024, Volume and Issue: 8(9), P. e8 - e8

Published: Aug. 12, 2024

Language: Английский

Citations

0