Genetic Polymorphisms in HMGCS1 Gene and Its Association with Slaughter Characteristics, Meat Quality, and Organ Coefficients in Guizhou White Goats

Animal Bioscience, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 16, 2025

This study aimed to identify polymorphisms in the gene encoding 3-hydroxy-3-methylglutaryl-CoA synthase 1, HMGCS1, and analyze their association with slaughter characteristics, meat quality, organ coefficients Guizhou white goats. A total of 153 twelve-month-old goats (78 male 75 female) were included study. Slaughter assessed. Association analyses between genotypes phenotypic traits conducted using a generalized linear model. Four polymorphic loci identified, i.e., g.15523T>C, g.15530G>C, g.18413T>C, g.19711G>A exons 5, 8, 9 HMGCS1 gene. Across all loci, males same genotype generally exhibited significantly better compared females (p < 0.05). At g.18413T>C locus, differences shear force observed within sex across different Organ higher The g.15523T>C g.15530G>C found strong linkage disequilibrium associated intramuscular fat content Fat diploid Hap2/2 individuals was than Hap1/1 Hap1/2 female CC showed levels dry matter other group. for liver hooves strongly linked could be used as molecular markers enhancing this trait goat breeding programs, fostering development production.

Language: Английский

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Effects of Dandelion Flavonoid Extract on the Accumulation of Flavonoids in Layer Hen Meat, Slaughter Performance and Blood Antioxidant Indicators of Spent Laying Hens

Animals, Journal Year: 2025, Volume and Issue: 15(6), P. 886 - 886

Published: March 20, 2025

This study aimed to investigate the effects of different supplemental amounts dandelion flavonoid extracts (DFE) in diets on nutrients chicken, slaughtering performance, blood biochemical indexes and antioxidant capacity spent laying hens. A total 180 560-day-old Hy-Line Brown hens were randomly divided into five groups. The control group was fed basal diet, while experimental groups supplemented with DFE at levels 1000, 2000, 4000, 8000 mg/kg (as T1, T2, T3, T4 group) respectively. variables measured included content flavonoids layer hen thigh meat breast meat, slaughter indexes, capacity. Data subjected a one-way analysis variance (one-way ANOVA) assess impact supplementation compared outcomes. results showed that dietary can increase meat. contents rutin 1.37, 4.41, 16.26, 36.03 ng/g, respectively, quercetin 2.58, 1.36, 4.98, 12.48 ng/g. In T4, 11.48, 15.98, 44.43, 122.32 9.96, 13.14, 23.15, 38.09 addition increased phenol feed highly significantly elevated (p < 0.01), chicken strongly positively correlated feed. decreased abdominal fat percentage 0.05) crude 0.05). reduced aspartate aminotransferase (AST) alanine (ALT) activities 0.05), triglyceride (TG), cholesterol (TC), low-density lipoprotein (LDL) (LDL-C), glucose (GLU), malondialdehyde (MDA) albumin (ALB), (T-AOC) superoxide dismutase (T-SOD), glutathione peroxidase (GSH-Px) activity Dietary concentrations could muscle hens, reduce rate effectively lipid levels, muscle, enhance body’s liver function.

Language: Английский

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A Comparison Between High- and Low-Performing Lambs and Their Impact on the Meat Quality and Development Level Using a Multi-Omics Analysis of Rumen Microbe–Muscle–Liver Interactions

Microorganisms, Journal Year: 2025, Volume and Issue: 13(4), P. 943 - 943

Published: April 19, 2025

Through an integrated multi-omics analysis of rumen microbial communities, muscle transcriptomes, metabolic profiles, and liver this study systematically compared high- low-performing lambs to elucidate their divergent effects on meat quality attributes growth development. A total 100 male with similar birth weight (3.07 ± 0.06 kg) were selected within 72 h. All test synchronized weaning at 45 days age uniformly fed the same diet (total mixed ration) in pen until 180 age, ad libitum access food water throughout period. Subsequently, eight highest (HADG) lowest (LADG) average daily gains slaughtered for performance evaluation analysis. This found that HADG increased body weight, fiber diameter, eye area, improved amino acid (histidine, arginine, valine, isoleucine, essential acid/total acid, acid/nonessential acid), fatty (linoleic behenic arachidonic acid) composition enhanced enzymes (pepsase, lipase, xylanase, amylase, carboxymethyl cellulose) promoted efficient fermentation (p < 0.05). Analysis populations indicated a notable increase Prevotella levels lambs. Furthermore, markers Schwartzia Streptococcus exhibited significant correlations differential traits. transcriptome correlation between turquoise module host phenotypes, particularly weight. Additionally, metabolism is primarily concentrated black module; however, it exhibits phenotype yellow Moreover, metabolites, microbes, phenotype, transcripts significantly correlated In conclusion, interactions among muscle, promote fermentation, which turn regulate transcriptional activity modify profiles both muscle. PCK1, SPP1, FGF7, NR4A1, DUSP5, GADD45B, etc., can be candidate genes finding provides theoretical basis further exploiting production potential Hu

Language: Английский

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Impact of anthocyanins derived from Dioscorea alata L. on growth performance, carcass characteristics, antioxidant capacity, and immune function of Hainan black goats

Frontiers in Veterinary Science, Journal Year: 2023, Volume and Issue: 10

Published: Nov. 21, 2023

Dioscorea alata L. anthocyanins (DAC) are natural compounds found in plants and have shown potential health benefits. The objective of this investigation was to assess the impact sourced from on growth, carcass traits, antioxidant potential, immune response Hainan black goats. In study, 30 three-month-old goats (with a weight 11.30 ± 0.82 kg) were selected randomly divided into two groups, with 15 each group. During 60-day experiment, control group (CON) treatment were, respectively, supplemented 0 40 mg/kg BW DAC basal diet. results showed that had no significant growth performance body characteristics ( p &gt; 0.05). However, terms meat quality, addition significantly increased pH value cooking yield 24 h post-slaughter &lt; 0.05), while reducing shear force Compared group, adding feed resulted increase total capacity (T-AOC) superoxide dismutase (T-SOD) concentrations plasma after days feeding After 60 feeding, T-AOC, T-SOD, glutathione peroxidase (GSH-Px), catalase (CAT) higher than concentration malondialdehyde (MDA) lower addition, supplementing content interleukin-10 (IL-10) immunoglobulin M (IgM) interleukin-6 (IL-6) G (IgG) IL-10 IL-1β, IL-6, tumor necrosis factor-α (TNF-α) suppressed summary, these indicate can improve enhance capacity, function

Language: Английский

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Effect of Feeding Level on Growth and Slaughter Performance, and Allometric Growth of Tissues and Organs in Female Growing Saanen Dairy Goats

Animals, Journal Year: 2024, Volume and Issue: 14(5), P. 730 - 730

Published: Feb. 27, 2024

This study aimed to investigate the effect of feeding level on growth and slaughter performance, allometric tissues organs in female growing dairy goats. The trial included 10–20 20–30 kg weight stages with 48 goat kids. 24 kids each stage were divided into 8 blocks based weight, 3 per block. Then, three from block randomly assigned one treatments, namely ad libitum (AL100), 70% (AL70), or 40% (AL40). was conducted when AL100 reached target 20 30 kg. results showed that ADG feed conversion rate a linear decline as decreased (p < 0.05). Compared AL70 groups, AL40 group exhibited lower shrunk body empty hot carcass net meat rate, visceral fat 0.05) both stages. Moreover, weights for skin mohair, blood, rumen, small intestine, large mammary gland, uterus than groups However, did not affect organ indices two > bone, mohair isometric (b ≈ 1), but muscle, fat, most internal positive 1) In conclusion, affects development goats, which vary depending specific organs.

Language: Английский

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Meta-analysis of dietary supplementation with flavonoids in small ruminants: Growth performance, antioxidant status, nutrient digestibility, ruminal fermentation, and meat quality

Small Ruminant Research, Journal Year: 2024, Volume and Issue: 241, P. 107401 - 107401

Published: Nov. 12, 2024

Language: Английский

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Effect of genetic variation in ACADM on slaughter and meat quality traits in Guizhou black goat

Small Ruminant Research, Journal Year: 2024, Volume and Issue: unknown, P. 107376 - 107376

Published: Sept. 1, 2024

Language: Английский

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Research advances in Pimpinella thellungiana: Nutrients, bioactive compounds, and functional properties benefitting livestock

Animal nutrition, Journal Year: 2024, Volume and Issue: 20, P. 239 - 248

Published: Nov. 28, 2024

Language: Английский

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Trends and Prospects of Lipophilic Bioactive Compounds in Meat Production and Preservation

Food Reviews International, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 19

Published: Dec. 30, 2024

Meat and meat products are important food sources of proteins, fatty acids, vitamins, minerals (iron zinc) for human beings. However, these nutritious meats vulnerable to quality deterioration including microbial contamination, protein lipid oxidation. Therefore, prevent postharvest changes in various chemicals, natural preservatives have been employed during processing. Natural can be hydrophilic or lipophilic compounds that support animal growth, preserve the by inhibiting oxidation contamination. Among these, applications product preservations extensively reviewed. recently, little no reviews reported on fat-soluble bioactive production preservation. Lipophilic bio-active such as omega-3 phytosterols, carotenoids, flavonoids, curcuminoids, etc. several preservation muscle foods. different growth promoters meat-producing animals agents enhancing storage reviewed this article. The inclusion improves rate meat.

Language: Английский

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Rutin alleviated lipopolysaccharide-induced damage in goat rumen epithelial cells

Animal Bioscience, Journal Year: 2023, Volume and Issue: 37(2), P. 303 - 314

Published: Oct. 27, 2023

Rutin, also called vitamin P, is a flavonoids from plants. Previous studies have indicated that rutin can alleviate the injury of tissues and cells by inhibiting oxidative stress ameliorating inflammation. There no report on protective effects goat rumen epithelial (GRECs) at present. Hence, we investigated whether lipopolysaccharide (LPS)-induced damage in GRECs.

Language: Английский

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