Behavioural Brain Research, Journal Year: 2024, Volume and Issue: 480, P. 115387 - 115387
Published: Dec. 5, 2024
Language: Английский
Published: Jan. 1, 2025
Language: Английский
Citations
0
Biomedical Reports, Journal Year: 2024, Volume and Issue: 21(5)
Published: Sept. 12, 2024
The present study assessed the behavior of morphine-addicted rats using behavioral video coding technology, to evaluate effective methods for identifying morphine addiction. Rats were divided into a control group (n=15) and addiction (n=15). model was established with 14-day increasing dose scheme, confirmed conditional place preference (CPP) experiment. After successful modeling, rats' recorded 12 h, then coded analyzed Observer XT analysis software. Compared group, showed increased heat pain tolerance time (P=0.039) spent more in white box during CPP experiment (P<0.001). Video revealed significant changes compared controls. In addition being lighter, decreased water intake, reduced licking forelimbs hind limbs, altered sleeping posture (sleeping curled up) day (all P<0.05). conclusion, chronic administration leads distinctive changes, including frequency, intake sleep posture. analysis, as safe non-invasive method, may provide convenient efficient approach studying rats.
Language: Английский
Citations
0
Der Nervenarzt, Journal Year: 2024, Volume and Issue: 95(9), P. 824 - 829
Published: July 31, 2024
Citations
0
Behavioural Brain Research, Journal Year: 2024, Volume and Issue: 480, P. 115387 - 115387
Published: Dec. 5, 2024
Language: Английский
Citations
0