Mechanisms of HIV-immunologic non-responses and research trends based on gut microbiota DOI Creative Commons
Xiangbin Sun,

Zhanpeng Xie,

Zhen Wu

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Dec. 26, 2024

With the increasing number of people with HIV (PWH) and use antiretroviral treatment (ART) for PWH, has gradually become a chronic infectious disease. However, some infected individuals develop issues immunologic non-responses (INRs) after receiving ART, which can lead to secondary infections seriously affect life expectancy quality PWH. Disruption gut microbiota is an important factor in immune activation inflammation HIV/AIDS, thus stabilizing reduce promoting reconstitution may direction HIV/AIDS. This paper, based on extensive literature review, summarizes definition, mechanisms, solutions INRs, starting from perspective microbiota.

Language: Английский

Mechanisms of HIV-immunologic non-responses and research trends based on gut microbiota DOI Creative Commons
Xiangbin Sun,

Zhanpeng Xie,

Zhen Wu

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Dec. 26, 2024

With the increasing number of people with HIV (PWH) and use antiretroviral treatment (ART) for PWH, has gradually become a chronic infectious disease. However, some infected individuals develop issues immunologic non-responses (INRs) after receiving ART, which can lead to secondary infections seriously affect life expectancy quality PWH. Disruption gut microbiota is an important factor in immune activation inflammation HIV/AIDS, thus stabilizing reduce promoting reconstitution may direction HIV/AIDS. This paper, based on extensive literature review, summarizes definition, mechanisms, solutions INRs, starting from perspective microbiota.

Language: Английский

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