Clinical, radiographical and histological evaluation of alveolar ridge preservation with different hydration methods of synthetic graft: a randomized controlled clinical trial

Deleted Journal, Journal Year: 2025, Volume and Issue: 9(1)

Published: Jan. 17, 2025

Alveolar ridge preservation (ARP) limits dimensional changes in alveolar bone after extraction. This study aims to evaluate tissue response biphasic-calcium-phosphate ceramics (BCP) with different hydration methodologies used for ARP. Sixty patients willing treatment were randomly allocated into two test groups and control. Test group-1 (n = 20) received graft hydrated saline ARP, whereas group-2 blood. In control 20), extraction sockets allowed heal without further intervention. Clinically (mesial height-MRH, distal height-DRH, width-RW) radiologically (Apico-coronal dimension-ACD) parameters recorded at baseline four months. Bone collected using trephine burs months was evaluated semi-quantitatively terms of histological immunohistochemical assess osteopontin (OPN) expression all groups. Based on the normality assumption MRH, DRH, RW ACD compared by a paired-t make comparison between initial 4-month values. The Kruskal-Wallis determine mean difference showed significant decrease (1.4 mm, p < 0.05), gain MRH (0.3 > 0.05) (0.775 loss DRH (1.5 vertical mesially (1.2 distally (0.74 but (0.21 (1.37 0.05). Immunohistochemistry analysis revealed newly formed bone, residual material well-vascularized uninflamed connective tissue. OPN significantly higher (p Our findings demonstrate that ARP BCP may depict horizontally vertically. highlights significance method clinically, histologically.

Language: Английский

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Research Progress on the Application of Autogenous Demineralized Dentin Matrix Particles for the Regeneration in Periodontitis Alveolar Defect

Science Discovery, Journal Year: 2025, Volume and Issue: 13(1), P. 1 - 5

Published: March 18, 2025

Demineralized Dentin Matrix (DDM) is derived from discarded human teeth and has a micro-nano structure with porous network. Its dentinal tubules are rich in various enzymes, antimicrobial peptides, cytokines such as BMP, IGFs, TGF - β, VEGF, IGF, etc., which can guide cells the alveolar fossa to grow into extraction socket form new bone, used for reconstruction of periodontal bone defects. DDM particles have advantages wide source, no immune rejection, simple production process, low cost. As ideal material, it expected become substitute traditional materials on transplantation. In this paper, different methods strategies regeneration defects were summarized, replacement combined barrier membrane, autologous blood clot, derivatives PRF CGF, other novel biological materials. Then, physicochemical properties granules, improved manufacturing process research status caused by periodontitis reviewed. Finally, limitations application future direction development proposed, order expect more evidence-based medical evidence clinical DDM.

Language: Английский

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Overbuilding techniques for thin buccal bone in immediate implant placement: an experimental study in dogs

Oral and Maxillofacial Surgery, Journal Year: 2025, Volume and Issue: 29(1)

Published: April 11, 2025

Language: Английский

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Mesh‐assisted regenerated site for alveolar ridge preservation: A case report

Clinical Advances in Periodontics, Journal Year: 2025, Volume and Issue: unknown

Published: April 20, 2025

Abstract Background The proposed technique utilizes the osteoconductive regenerative properties of bone‐substitute materials (BSMs) and space‐maintaining function titanium mesh to restore alveolar ridge at extraction sites with lost labial plates in a single procedure. This approach may reduce need for extensive augmentation procedures, shorten treatment duration, minimize complications, potentially lower overall costs patients. Methods Both patients presented hopeless dentition, characterized by chronic infection loss plates. To regenerate ridge, was utilized combination layered application xenograft allograft BSMs. success this depended on stabilization, thorough site debridement, absence soft‐tissue tension. Results effectively restored regenerated sufficient bone accommodate dental implants. Significant regeneration achieved both cases, minimal complications. In one case, minor exposure occurred; however, it did not affect healing managed during re‐entry surgery. Conclusion It represents novel preservation plates, even presence infection. However, future studies sound methodology, larger sample sizes, long follow‐up periods are recommended validate these findings. Key points Mesh‐Assisted Regenerated Site (MARS) restores combining substitutes augmentation, long‐term costs. depends minimally traumatic extraction, meticulous socket careful soft tissue management, precise placement under optimal magnification. Although effective, has limitations, including potential vertical loss, time‐consuming possible additional occasional challenges retrieval, risk, all which compromise implant success. Proper case selection essential mitigate optimize clinical outcomes. Plain language summary When teeth removed, surrounding can shrink. Techniques preserve area, known as preservation, help prevent shrinkage. uses specialized rebuild areas where front portion is missing. author used bone. steps included stabilizing mesh, thoroughly cleaning out any infection, layering materials, ensuring gum overly tight. successfully reconstructed missing bone, making place standard cases showed significant growth issues. small part exposed but impact addressed rebuilt long‐standing shows promise preserving regenerating areas, more needed confirm results improve method.

Language: Английский

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Biomaterials and therapeutic strategies designed for tooth extraction socket healing.

Biomaterials, Journal Year: 2024, Volume and Issue: 316, P. 122975 - 122975

Published: Nov. 29, 2024

Language: Английский

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Changes of the Alveolar Bone Ridge Using Bone Mineral Grafts and Collagen Membranes after Tooth Extraction: A Systematic Review and Meta-Analysis

Bioengineering, Journal Year: 2024, Volume and Issue: 11(6), P. 565 - 565

Published: June 3, 2024

Background: Alveolar preservation techniques for esthetic or functional purposes, both, are a frequently used alternative the treatment of post-extraction sockets, aim which is regeneration lesion and alveolar bone crest. Methods: Studies published in PubMed (Medline), Web Science, Embase, Cochrane Library databases up to January 2024 were consulted. Inclusion criteria established as intervention studies, according PICOs strategy: adult subjects undergoing dental extractions (participants), with alveoli treated mineral grafts collagen membranes (intervention), compared spontaneous healing (comparison), observing response clinical radiological measures crest (outcomes). Results: We obtained 561 results selected 12 studies. Risk bias was assessed using Bias Tool, methodological quality Joanna Briggs Institute. Due high heterogeneity studies (I2 > 75%), random-effects meta-analysis used. Despite trend, no statistical significance (p 0.05) found experimental groups. Conclusions: The use combination resorbable barriers provides greater ridge, although more needed.

Language: Английский

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Alveolar ridge preservation at molar extraction sites: A systematic review and meta-analysis

Journal of Evidence Based Dental Practice, Journal Year: 2024, Volume and Issue: 25(1), P. 102074 - 102074

Published: Nov. 27, 2024

Language: Английский

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Pre-extraction alveolar buccal bone overbuilding: a preclinical investigation

Oral and Maxillofacial Surgery, Journal Year: 2024, Volume and Issue: 29(1)

Published: Dec. 28, 2024

Language: Английский

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Socket Preservation Technique Using Resorbable Collagen Membrane v/s High Density d-PTFE Membrane: A Must in today’s Implant Rehabilitations. A Literature Review and 2 Clinical Cases Report.

SVOA Dentistry, Journal Year: 2024, Volume and Issue: 5(1), P. 19 - 25

Published: Jan. 29, 2024

Following tooth extraction, resorption in alveolar bone results narrowing of remaining ridge the extraction site leading to compromised functional and aesthetic outcomes. The overall goal present article is shed light on importance socket preservation procedure preserving original dimensional contours, while comparing two essential approaches, using non-resorbable high density d-PTFE membranes v/s non-cross linked collagen resorbable membranes, by assessing clinical terms regenerated volume, postoperative complications evaluation keratinized tissue grafted areas with either one above mentioned membranes.

Language: Английский

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Pre-extraction Alveolar Buccal Bone Overbuilding: A Preclinical Investigation

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: July 18, 2024

Background: The pre-extraction overbuilding procedure was designed with the intent to mitigate buccal bone resorption following tooth extraction. This study aimed address this gap by comparing efficacy of and juxta-extraction treatments in preserving volume Material Methods: At test sites (pre-extraction sites), an alveolar crest performed on aspect distal root fourth premolar using a xenograft covered collagen membrane. No treatment applied at control sites. After 3 months, roots both premolars were extracted alveoli filled collagenated xenograft. An overbuilt also (juxta-extraction sites). biopsies collected. Results: at clinical evaluation, apical lingual 1.4 mm 1.2 sites, respectively. At histological 3.2 3.3 New originated from residual pre-existing attempt restore original dimension. Conclusion: the procedures conducted before time extraction did not aid crest. Nevertheless, indications ongoing regeneration evident within augmented space maintained biomaterial, suggesting that prolonged healing might be required attain optimal outcomes.

Language: Английский

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