Piezo Ion Channels and Their Association With Haptic Technology Use: A Narrative Review

Cureus, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 14, 2025

The recent identification of Piezo ion channels demonstrating a mechano-sensitive impact on neurons revealed distinct Piezo-1 and 2 types. While predominates in linked to non-sensory stimulation, such as pressure blood vessels, Piezo-2 sensory touch. have major bidirectional transient receptor potential (TRP) channels, TRPs also neurotransmitter release. Particularly existent dorsal root ganglion (DRG) neurons, which are located nerve endings, is key DRG activator. Subsequent findings been vital medical haptic technology developments, tandem with breakthroughs the emerging neurology subfield connectomics plus AI developments. Included this review historical overview, interrelationship TRPs, inclusive TRPV1/TRPV8, rehab technology, focus use stroke survivor pain mitigation, development patch aimed at alleviating and/or anxiety. Neurogenic resulting from hyperalgesia/allodynia survivors target for drugs haptics reduction; patients experiencing neuropathic or psychosomatic other prime targets. Increased knowledge may promote more precisely targeted therapeutic

Language: Английский

Emerging roles of mechanically activated ion channels in autoimmune disease

Autoimmunity Reviews, Journal Year: 2025, Volume and Issue: 24(7), P. 103813 - 103813

Published: April 7, 2025

Language: Английский