Causal associations between posttraumatic stress disorder and type 2 diabetes

Diabetology & Metabolic Syndrome, Journal Year: 2025, Volume and Issue: 17(1)

Published: Feb. 19, 2025

Posttraumatic stress disorder (PTSD) patients have a high comorbidity with type 2 diabetes (T2D). Whether PTSD influences the risk of is still not known. We used GWAS data from European ancestry (23,121 cases and 151,447 controls) T2D (80,154 853,816 to investigate bidirectional associations between by Mendelian randomization (MR) analysis. showed that was causally associated higher odds (OR = 1.04, 95% CI: 1.01–1.06, P 0.0086), but vice versa. Our study suggests may increase T2D. sufferers should be screened for its precursor known as metabolic syndrome.

Language: Английский

Bidirectional causal effects between bipolar disorder and immune cell traits

Journal of Affective Disorders, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский