Evolutionary Origins and Adaptive Significance of A‐to‐I RNA Editing in Animals and Fungi DOI Open Access
Yanfei Du, Chenhui Wang, Yu Zhang

et al.

BioEssays, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

ABSTRACT Adenosine‐to‐inosine (A‐to‐I) RNA editing, capable of protein recoding, has evolved independently in animals and fungi. This study proposes adaptive hypotheses regarding its origins phenotypic significance, suggesting that A‐to‐I editing enhances adaptability by alleviating genetic trade‐offs. In metazoans, emergence may have been driven a development‐defense trade‐off associated with transposable element activation during the evolution multicellularity. Late Devonian cooling End‐Permian warming are hypothesized to extensive recoding coleoid nervous systems Sordariomycete sexual fruiting bodies, respectively. These adaptations influenced key evolutionary innovations, including metazoan systems, intelligence, shell loss, fungal reproductive structures. Additionally, is proposed facilitate accelerated development specific life‐history strategies both paper provides new perspectives on forces shaping role diversity across taxa.

Language: Английский

Evolutionary Origins and Adaptive Significance of A‐to‐I RNA Editing in Animals and Fungi DOI Open Access
Yanfei Du, Chenhui Wang, Yu Zhang

et al.

BioEssays, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

ABSTRACT Adenosine‐to‐inosine (A‐to‐I) RNA editing, capable of protein recoding, has evolved independently in animals and fungi. This study proposes adaptive hypotheses regarding its origins phenotypic significance, suggesting that A‐to‐I editing enhances adaptability by alleviating genetic trade‐offs. In metazoans, emergence may have been driven a development‐defense trade‐off associated with transposable element activation during the evolution multicellularity. Late Devonian cooling End‐Permian warming are hypothesized to extensive recoding coleoid nervous systems Sordariomycete sexual fruiting bodies, respectively. These adaptations influenced key evolutionary innovations, including metazoan systems, intelligence, shell loss, fungal reproductive structures. Additionally, is proposed facilitate accelerated development specific life‐history strategies both paper provides new perspectives on forces shaping role diversity across taxa.

Language: Английский

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