Nature Cardiovascular Research,
Journal Year:
2023,
Volume and Issue:
2(4), P. 351 - 367
Published: April 3, 2023
The
leading
cause
of
death
in
the
world,
cardiovascular
disease
(CVD),
remains
a
formidable
condition
for
researchers,
clinicians
and
patients
alike.
CVD
comprises
broad
collection
diseases
spanning
heart,
vasculature
blood
that
runs
through
interconnects
them.
Limitations
therapeutic
diagnostic
landscapes
have
generated
excitement
advances
nanomedicine,
field
focused
on
improving
patient
outcomes
transformative
therapies,
imaging
agents
ex
vivo
diagnostics.
nanomedicines
are
fundamentally
shaped
by
their
intended
clinical
application,
including
(1)
cardiac
or
heart-related
biomaterials,
which
can
be
functionally
(for
example,
mechanically,
immunologically,
electrically)
improved
incorporating
nanomaterials;
(2)
vasculature,
involving
systemically
injected
nanotherapeutics
nanodiagnostics,
nano-enabled
biomaterials
tissue-nanoengineered
solutions;
(3)
sensitivity
and/or
specificity
devices
samples.
While
immunotherapy
has
developed
into
key
pillar
oncology
past
dozen
years,
immunoimaging
recently
emergent
likely
to
factor
substantially
management
coming
decade.
nanomaterials
CVD-related
trials
many
promising
preclinical
strategies
indicate
nanomedicine
is
cusp
greatly
impacting
with
CVD.
Here
we
review
these
recent
advances,
highlighting
opportunities
rapidly
emerging
nanomedicine.
Healthcare,
Journal Year:
2023,
Volume and Issue:
11(6), P. 887 - 887
Published: March 19, 2023
ChatGPT
is
an
artificial
intelligence
(AI)-based
conversational
large
language
model
(LLM).
The
potential
applications
of
LLMs
in
health
care
education,
research,
and
practice
could
be
promising
if
the
associated
valid
concerns
are
proactively
examined
addressed.
current
systematic
review
aimed
to
investigate
utility
highlight
its
limitations.
Using
PRIMSA
guidelines,
a
search
was
conducted
retrieve
English
records
PubMed/MEDLINE
Google
Scholar
(published
research
or
preprints)
that
context
practice.
A
total
60
were
eligible
for
inclusion.
Benefits
cited
51/60
(85.0%)
included:
(1)
improved
scientific
writing
enhancing
equity
versatility;
(2)
(efficient
analysis
datasets,
code
generation,
literature
reviews,
saving
time
focus
on
experimental
design,
drug
discovery
development);
(3)
benefits
(streamlining
workflow,
cost
saving,
documentation,
personalized
medicine,
literacy);
(4)
education
including
learning
critical
thinking
problem-based
learning.
Concerns
regarding
use
stated
58/60
(96.7%)
ethical,
copyright,
transparency,
legal
issues,
risk
bias,
plagiarism,
lack
originality,
inaccurate
content
with
hallucination,
limited
knowledge,
incorrect
citations,
cybersecurity
infodemics.
can
induce
paradigm
shifts
However,
embrace
this
AI
chatbot
should
extreme
caution
considering
As
it
currently
stands,
does
not
qualify
listed
as
author
articles
unless
ICMJE/COPE
guidelines
revised
amended.
An
initiative
involving
all
stakeholders
urgently
needed.
This
will
help
set
ethics
guide
responsible
among
other
academia.
BMC Medical Education,
Journal Year:
2023,
Volume and Issue:
23(1)
Published: Sept. 22, 2023
Abstract
Introduction
Healthcare
systems
are
complex
and
challenging
for
all
stakeholders,
but
artificial
intelligence
(AI)
has
transformed
various
fields,
including
healthcare,
with
the
potential
to
improve
patient
care
quality
of
life.
Rapid
AI
advancements
can
revolutionize
healthcare
by
integrating
it
into
clinical
practice.
Reporting
AI’s
role
in
practice
is
crucial
successful
implementation
equipping
providers
essential
knowledge
tools.
Research
Significance
This
review
article
provides
a
comprehensive
up-to-date
overview
current
state
practice,
its
applications
disease
diagnosis,
treatment
recommendations,
engagement.
It
also
discusses
associated
challenges,
covering
ethical
legal
considerations
need
human
expertise.
By
doing
so,
enhances
understanding
significance
supports
organizations
effectively
adopting
technologies.
Materials
Methods
The
investigation
analyzed
use
system
relevant
indexed
literature,
such
as
PubMed/Medline,
Scopus,
EMBASE,
no
time
constraints
limited
articles
published
English.
focused
question
explores
impact
applying
settings
outcomes
this
application.
Results
Integrating
holds
excellent
improving
selection,
laboratory
testing.
tools
leverage
large
datasets
identify
patterns
surpass
performance
several
aspects.
offers
increased
accuracy,
reduced
costs,
savings
while
minimizing
errors.
personalized
medicine,
optimize
medication
dosages,
enhance
population
health
management,
establish
guidelines,
provide
virtual
assistants,
support
mental
care,
education,
influence
patient-physician
trust.
Conclusion
be
used
diagnose
diseases,
develop
plans,
assist
clinicians
decision-making.
Rather
than
simply
automating
tasks,
about
developing
technologies
that
across
settings.
However,
challenges
related
data
privacy,
bias,
expertise
must
addressed
responsible
effective
healthcare.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(7), P. 1916 - 1916
Published: July 10, 2023
Artificial
intelligence
(AI)
has
emerged
as
a
powerful
tool
that
harnesses
anthropomorphic
knowledge
and
provides
expedited
solutions
to
complex
challenges.
Remarkable
advancements
in
AI
technology
machine
learning
present
transformative
opportunity
the
drug
discovery,
formulation,
testing
of
pharmaceutical
dosage
forms.
By
utilizing
algorithms
analyze
extensive
biological
data,
including
genomics
proteomics,
researchers
can
identify
disease-associated
targets
predict
their
interactions
with
potential
candidates.
This
enables
more
efficient
targeted
approach
thereby
increasing
likelihood
successful
approvals.
Furthermore,
contribute
reducing
development
costs
by
optimizing
research
processes.
Machine
assist
experimental
design
pharmacokinetics
toxicity
capability
prioritization
optimization
lead
compounds,
need
for
costly
animal
testing.
Personalized
medicine
approaches
be
facilitated
through
real-world
patient
leading
effective
treatment
outcomes
improved
adherence.
comprehensive
review
explores
wide-ranging
applications
delivery
form
designs,
process
optimization,
testing,
pharmacokinetics/pharmacodynamics
(PK/PD)
studies.
an
overview
various
AI-based
utilized
technology,
highlighting
benefits
drawbacks.
Nevertheless,
continued
investment
exploration
industry
offer
exciting
prospects
enhancing
processes
care.
Polymers,
Journal Year:
2021,
Volume and Issue:
13(9), P. 1499 - 1499
Published: May 6, 2021
Polymer
3D
printing
is
an
emerging
technology
with
recent
research
translating
towards
increased
use
in
industry,
particularly
medical
fields.
advantageous
because
it
enables
low-cost
functional
parts
diverse
properties
and
capabilities.
Here,
we
provide
a
review
of
advances
for
polymer
by
investigating
related
to
materials,
processes,
design
strategies
applications.
Research
materials
has
led
the
development
polymers
characteristics
mechanics
biocompatibility,
tuning
mechanical
achieved
altering
process
parameters.
Suitable
processes
include
extrusion,
resin,
powder
printing,
which
enable
directed
material
deposition
customized
architectures.
Design
strategies,
such
as
hierarchical
distribution
balancing
conflicting
properties,
biological
needs
tissue
scaffolds.
Further
applications
reviewed
safety
equipment,
dental
implants,
drug
delivery
systems,
findings
suggesting
need
improved
methods
navigate
complex
decision
space
enabled
printing.
across
these
areas
will
lead
continued
improvement
3D-printed
performance
that
essential
advancing
frontiers
engineering
medicine.
PLOS Digital Health,
Journal Year:
2023,
Volume and Issue:
2(6), P. e0000278 - e0000278
Published: June 22, 2023
The
adoption
of
artificial
intelligence
(AI)
algorithms
is
rapidly
increasing
in
healthcare.
Such
may
be
shaped
by
various
factors
such
as
social
determinants
health
that
can
influence
outcomes.
While
AI
have
been
proposed
a
tool
to
expand
the
reach
quality
healthcare
underserved
communities
and
improve
equity,
recent
literature
has
raised
concerns
about
propagation
biases
disparities
through
implementation
these
algorithms.
Thus,
it
critical
understand
sources
bias
inherent
AI-based
This
review
aims
highlight
potential
within
each
step
developing
healthcare,
starting
from
framing
problem,
data
collection,
preprocessing,
development,
validation,
well
their
full
implementation.
For
steps,
we
also
discuss
strategies
mitigate
disparities.
A
checklist
was
developed
with
recommendations
for
reducing
during
development
stages.
It
important
developers
users
keep
considerations
mind
advance
equity
all
populations.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Feb. 21, 2023
Abstract
An
artificial
intelligence
(AI)-based
conversational
large
language
model
(LLM)
was
launched
in
November
2022
namely,
“ChatGPT”.
Despite
the
wide
array
of
potential
applications
LLMs
healthcare
education,
research
and
practice,
several
valid
concerns
were
raised.
The
current
systematic
review
aimed
to
investigate
possible
utility
ChatGPT
highlight
its
limitations
practice.
Using
PRIMSA
guidelines,
a
search
conducted
retrieve
English
records
PubMed/MEDLINE
Google
Scholar
under
term
Eligibility
criteria
included
published
or
preprints
any
type
that
discussed
context
A
total
280
identified,
following
full
screening,
60
eligible
for
inclusion.
Benefits/applications
cited
51/60
(85.0%)
with
most
common
being
scientific
writing
followed
by
benefits
(efficient
analysis
massive
datasets,
code
generation
rapid
concise
literature
reviews
besides
drug
discovery
development).
Benefits
practice
cost
saving,
documentation,
personalized
medicine
improved
health
literacy.
Concerns/possible
risks
use
expressed
58/60
(96.7%)
ethical
issues
including
risk
bias,
plagiarism,
copyright
issues,
transparency
legal
lack
originality,
incorrect
responses,
limited
knowledge,
inaccurate
citations.
promising
which
can
result
paradigm
shifts
embrace
this
application
should
be
done
extreme
caution.
Specific
education
include
learning
tools
shift
towards
more
focus
on
critical
thinking
problem-based
learning.
In
valuable
streamlining
workflow
refining
medicine.
Saving
time
experimental
design
enhancing
equity
versatility
are
research.
Regarding
authorship
articles,
as
it
currently
stands,
does
not
qualify
listed
an
author
unless
ICMJE/COPE
guidelines
revised
amended.
initiative
involving
all
stakeholders
involved
is
urgently
needed
set
ethics
conduct
responsible
practices
among
other
LLMs.
Bioengineering,
Journal Year:
2024,
Volume and Issue:
11(4), P. 337 - 337
Published: March 29, 2024
As
healthcare
systems
around
the
world
face
challenges
such
as
escalating
costs,
limited
access,
and
growing
demand
for
personalized
care,
artificial
intelligence
(AI)
is
emerging
a
key
force
transformation.
This
review
motivated
by
urgent
need
to
harness
AI’s
potential
mitigate
these
issues
aims
critically
assess
integration
in
different
domains.
We
explore
how
AI
empowers
clinical
decision-making,
optimizes
hospital
operation
management,
refines
medical
image
analysis,
revolutionizes
patient
care
monitoring
through
AI-powered
wearables.
Through
several
case
studies,
we
has
transformed
specific
domains
discuss
remaining
possible
solutions.
Additionally,
will
methodologies
assessing
solutions,
ethical
of
deployment,
importance
data
privacy
bias
mitigation
responsible
technology
use.
By
presenting
critical
assessment
transformative
potential,
this
equips
researchers
with
deeper
understanding
current
future
impact
on
healthcare.
It
encourages
an
interdisciplinary
dialogue
between
researchers,
clinicians,
technologists
navigate
complexities
implementation,
fostering
development
AI-driven
solutions
that
prioritize
standards,
equity,
patient-centered
approach.
Frontiers in Artificial Intelligence,
Journal Year:
2023,
Volume and Issue:
6
Published: Aug. 29, 2023
As
the
demand
for
quality
healthcare
increases,
systems
worldwide
are
grappling
with
time
constraints
and
excessive
workloads,
which
can
compromise
of
patient
care.
Artificial
intelligence
(AI)
has
emerged
as
a
powerful
tool
in
clinical
medicine,
revolutionizing
various
aspects
care
medical
research.
The
integration
AI
medicine
not
only
improved
diagnostic
accuracy
treatment
outcomes,
but
also
contributed
to
more
efficient
delivery,
reduced
costs,
facilitated
better
experiences.
This
review
article
provides
an
extensive
overview
applications
history
taking,
examination,
imaging,
therapeutics,
prognosis
Furthermore,
it
highlights
critical
role
played
transforming
developing
nations.
Plants,
Journal Year:
2023,
Volume and Issue:
12(17), P. 3077 - 3077
Published: Aug. 28, 2023
Undoubtedly,
the
advent
of
antibiotics
in
19th
century
had
a
substantial
impact,
increasing
human
life
expectancy.
However,
multitude
scientific
investigations
now
indicate
that
we
are
currently
experiencing
phase
known
as
post-antibiotic
era.
There
is
genuine
concern
might
regress
to
time
before
and
confront
widespread
outbreaks
severe
epidemic
diseases,
particularly
those
caused
by
bacterial
infections.
These
have
demonstrated
epidemics
thrive
under
environmental
stressors
such
climate
change,
depletion
natural
resources,
detrimental
activities
wars,
conflicts,
antibiotic
overuse,
pollution.
Moreover,
bacteria
possess
remarkable
ability
adapt
mutate.
Unfortunately,
current
development
insufficient,
future
appears
grim
unless
abandon
our
approach
generating
synthetic
rapidly
lose
their
effectiveness
against
multidrug-resistant
bacteria.
Despite
vital
role
modern
medicine,
medicinal
plants
served
primary
source
curative
drugs
since
ancient
times.
Numerous
reports
published
over
past
three
decades
suggest
could
serve
promising
alternative
ineffective
combating
infectious
diseases.
Over
few
years,
phenolic
compounds,
alkaloids,
saponins,
terpenoids
exhibited
noteworthy
antibacterial
potential,
primarily
through
membrane-disruption
mechanisms,
protein
binding,
interference
with
intermediary
metabolism,
anti-quorum
sensing,
anti-biofilm
activity.
optimize
utilization
effective
drugs,
further
advancements
omics
technologies
network
pharmacology
will
be
required
order
identify
optimal
combinations
among
these
compounds
or
conjunction
antibiotics.