Deep Learning Estimation of 10-2 and 24-2 Visual Field Metrics Based on Thickness Maps from Macula OCT

Ophthalmology, Journal Year: 2021, Volume and Issue: 128(11), P. 1534 - 1548

Published: April 23, 2021

Language: Английский

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Viability of Performing Multiple 24-2 Visual Field Examinations at the Same Clinical Visit: The Frontloading Fields Study (FFS)

American Journal of Ophthalmology, Journal Year: 2021, Volume and Issue: 230, P. 48 - 59

Published: May 2, 2021

To assess the viability, in terms of time taken for testing and repeatability, frontloading (performing multiple perimetric examinations) a single clinic visit.Reliability enhancement analysis.A total 329 healthy glaucoma suspect subjects within undergoing using SITA-Faster twice each eye same session were included. Global indices, pointwise sensitivity probability scores, test duration, reliability metrics analysed.For both tests 9.1% right 6.7% left results unreliable, with 58.4% 67.5% eyes achieving reliable results, respectively; 83.8% all spent less than 20 minutes performing tests. Differences global scores showed no systematic or clinically significant difference between one two eye. There was also number locations identified as defective at P < .05 level Test that unreliable tended to show more instances failed "cluster" criterion not repeatable.Frontloading viable obtaining sets reliable, repeatable data conventional outputs, overcoming practical issues regarding low singleton confirmation visual field defects. Despite need remain cognisant SITA-Faster, this algorithm may be method meeting recommendations required make confident inferences about state progression.

Language: Английский

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Measures of disease activity in glaucoma

Biosensors and Bioelectronics, Journal Year: 2021, Volume and Issue: 196, P. 113700 - 113700

Published: Oct. 12, 2021

Language: Английский

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The Frontloading Fields Study: The Impact of False Positives and Seeding Point Errors on Visual Field Reliability When Using SITA-Faster

Translational Vision Science & Technology, Journal Year: 2022, Volume and Issue: 11(2), P. 20 - 20

Published: Feb. 10, 2022

The purpose of this study was to evaluate the impact two conventional reliability criteria (false positives [FPs] and seeding point errors [SPEs]) concurrent effect low sensitivity points (≤19 dB) on intrasession SITA-Faster visual field (VF) result correlations.There were 2320 VF results from 1160 eyes healthy, glaucoma suspects, subjects with that separated into "both reliable" or "reliable-unreliable" pairs. (mean deviation pointwise sensitivity) analyzed against spectrum FP rates SPE, without censorship ≤19 dB. Segmental linear regression used identify critical where significantly different between tests due levels.There a significant, but small (0.09 dB per 1% exceeding 12%) increase in mean deviation, an number showing >3 (0.25-0.28 locations 12%). SPEs almost exclusively related decrease at primary did not significant differences other indices. Censoring improved correlation reliable unreliable results.Current for judging (FP rate >15% SPE) can lead data being erroneously excluded, as many do show compared those deemed "reliable." improves correlations results.We provide guidelines assessing FP, interpretation.

Language: Английский

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The frontloading approach to meet guideline-recommended visual field testing for glaucoma: time and cost

Ophthalmology Glaucoma, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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Management of open‐angle glaucoma by primary eye‐care practitioners: toward a personalised medicine approach

Clinical and Experimental Optometry, Journal Year: 2020, Volume and Issue: 104(3), P. 367 - 384

Published: Aug. 18, 2020

Glaucoma is the leading cause of irreversible blindness worldwide. As a chronic disease, glaucoma presents significant burden to individual, health‐care provider and system. Currently, strategies for treating are focused on lowering intraocular pressure, which aimed at slowing or arresting disease progression over time. This only current accepted therapeutic strategy glaucoma, can be achieved using topical drugs, laser trabeculoplasty, filtration surgery cyclodestructive techniques. The pressure has been well‐supported by numerous large‐scale seminal clinical trials in primary open‐angle both its early advanced stages. Although such guidance remains current, last 10-years, there evolution preferred first‐line therapies treatment with resultant shift practice patterns, particularly course disease. These changes reflect from perspective doctor – titrating most effective least risky modality patient, consenting that preserves vision results minimal negative impact quality life. In this review, recent evidence regarding modalities presented an updated framework management proposed.

Language: Английский

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Visualizing the Consistency of Clinical Characteristics that Distinguish Healthy Persons, Glaucoma Suspect Patients, and Manifest Glaucoma Patients

Ophthalmology Glaucoma, Journal Year: 2020, Volume and Issue: 3(4), P. 274 - 287

Published: April 27, 2020

To use factor analysis to visualize and assess the reproducibility consistency of clinical quantitative parameters that can optimally distinguish among healthy, glaucoma suspect, manifest patients at a cross-sectional level thus describe transition change diagnostic categories.Retrospective study.The medical records (diagnosed by expert clinicians) seen Centre for Eye Health in 2015 (n = 148, n 664, 129, respectively) 2018 242, 464, 126, were reviewed. One eye was selected study.Quantitative measures (intraocular pressure [IOP], central corneal thickness [CCT], visual field [VF], OCT) extracted binary logistic (backward stepwise) regression performed identify factors dictated separation between pairs. These used systematically as inputs determine final model could potentially predict diagnosis.Intraocular pressure, CCT, VF (mean deviation pattern standard deviation) indices, OCT optic nerve head values (retinal fiber layer [RNFL] ganglion cell-inner plexiform layer).Few identified commonly significant across all pairings (3 23: IOP, deviation, 7-o'clock RNFL thickness) (1 vertical cup-to-disc ratio). Few overlapped when comparing results, highlighting inconsistencies models years. Factor showed good healthy persons patients. Using biplots data 2-dimensional clusters, suspect demonstrated substantial overlap with cohorts. The contributions each parameter changed groups years.Despite advances ocular imaging perimetry, remains confounded lack consistent, reproducible combinations criteria. results highlight nebulousness (at patient-, instrument-, clinician-related levels) diagnosis contingent on individual expertise assessment.

Language: Английский

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Current Challenges Supporting School-Aged Children with Vision Problems: A Rapid Review

Applied Sciences, Journal Year: 2021, Volume and Issue: 11(20), P. 9673 - 9673

Published: Oct. 17, 2021

Many children have undetected vision problems or insufficient visual information processing that may be a factor in lower academic outcomes. The aim of this paper is to contribute better understanding the importance screening for school-aged children, and investigate possibilities how eye-tracking (ET) technologies can support this. While there are indications these screening, broad apply them by whom, if it possible utilize at schools, lacking. We review interdisciplinary research on performing investigations, discuss current challenges technology support. focus exploring ET handling disorders, especially non-vision experts. data orginate from literature survey peer-reviewed journals conference articles complemented secondary sources, following rapid methodology. highlight trends supportive identify involved stakeholders studies develop more training non-experts.

Language: Английский

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Comparing a head‐mounted virtual reality perimeter and the Humphrey Field Analyzer for visual field testing in healthy and glaucoma patients

Ophthalmic and Physiological Optics, Journal Year: 2023, Volume and Issue: 44(1), P. 83 - 95

Published: Oct. 6, 2023

Abstract Purpose To compare clinical visual field outputs in glaucoma and healthy patients returned by the Humphrey Field Analyzer (HFA) virtual reality (Virtual Field, VF) perimetry. Methods One eye of 54 41 subjects was prospectively tested (three times each random order) using HFA VF perimeters (24‐2 test grids). We extracted compared global indices (mean deviation [MD] pattern standard [PSD]), pointwise sensitivity (and calculated ‘equivalent’ after accounting for differences background luminance) defects. Bland–Altman difference [ M diff ] 95% limits agreement [LoA]) intraclass correlation analyses were performed. Results The shorter (by 76 s) had lower fixation losses 0.08) false‐positive rate 0.01) to (all p < 0.0001). Intraclass correlations 0.86, 0.82 0.47 MD, PSD between devices, respectively. Test–retest variability higher ( 0.3 dB, LoA −7.6 8.2 dB) −0.3 −6.4 5.9 dB), indicating greater test–retest variability. When device's underlying normative database, detected, on average, 7 more defects (at 0.05 level) out 52 locations this iteration cohort. Conclusions Virtual returns results that are correlated with HFA, but sensitivities variable. Differences defect detection its current database raise questions about widespread adoption lieu HFA.

Language: Английский

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Frontloading visual field tests detect earlier mean deviation progression when applied to real‐world‐derived early‐stage glaucoma data

Ophthalmic and Physiological Optics, Journal Year: 2024, Volume and Issue: 44(2), P. 426 - 441

Published: Jan. 16, 2024

Abstract Purpose To examine the diagnostic accuracy of performing two (frontloaded) versus one (clinical standard) visual field (VF) test per visit for detecting progression early glaucoma in data derived from clinical populations. Methods A computer simulation model was used to follow VFs 10,000 patients (derived cohorts: Heijl et al., Swedish cohort; and Chauhan Canadian Glaucoma Study [CGS]) over a 10‐year period identify whose mean deviation (MD) detected. Core (baseline MD rates) were extracted studies cohorts glaucoma, which modulated using SITA‐Faster variability characteristics previous work. Additional variables included follow‐up intervals (six‐monthly or yearly) rates perimetric loss any reason (0%, 15% 30%). The main outcome measures proportions progressors Results When cohort reviewed six‐monthly, frontloaded strategy detected more compared non‐frontloaded method up years 8, 9 10 0%, 30% conditions. time required detect 50% cases 1.0–1.5 less frontloading non‐frontloading. At 4 years, increased detection by 26.7%, 28.7% 32.4% conditions, respectively. Where both techniques progression, earlier (78.5%–81.5% 1.0–1.3 when six‐monthly; 81%–82.9% 1.2–2.1 yearly). Accordingly, these had severe scores review: 0.63–1.67 dB ‘saved’; yearly 1.10–2.87 dB). differences with higher loss. Similar tendencies noted applied CGS cohort. Conclusions Frontloaded distributions led progression.

Language: Английский

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