Association between life’s crucial 9 and severe abdominal aortic calcification in U.S. Adults: the mediating role of the systemic inflammatory response index

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: Feb. 28, 2025

Background Life’s Crucial 9 (LC9) is an emerging cardiovascular health scoring system that incorporates Essential 8 (LE8) alongside mental factors. However, its relationship with severe abdominal aortic calcification (SAAC) remains poorly understood. Objectives The objective of this study to investigate the between LC9 scores and incidence SAAC in US population. Methods Data from 2,323 participants were analyzed, originating 2013-2014 National Health Nutrition Examination Survey (NHANES) cycle. In exploring dynamics LC9, constituents, their SAAC, we employed advanced statistical methodologies, specifically multivariable logistic regression weighted quantile sum regression. Subgroup interaction analyses conducted reinforce conclusions, mediation analysis was how systemic inflammatory response index (SIRI) influences connection SAAC. Results fully adjusted models, increase 10 points associated a 26% reduction prevalence achieving significance ( P < 0.001). As increased, significant decline noted 0.05). WQS pinpointed strong links occurrence variables including exposure tobacco, blood pressure levels, glucose concentrations, status, odds ratio stood at 0.244, 95% CI extending 0.119 0.495. SIRI positively correlated 0.05) decreased rising (β = -0.09, Mediation revealed significantly influenced linkage accounting for 5.8% effect, statistically p-value Conclusion This research highlights robust inverse elevated reduced incidence, suggesting role as key factor diminishing frequency Furthermore, mediates relationship.

Language: Английский

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Evaluating the Incremental Value of an Expanded Cardiovascular Health Score for the Prevalence of Abdominal Aortic Calcification Among Middle-aged and Elderly Individuals

International Journal of Cardiology Cardiovascular Risk and Prevention, Journal Year: 2025, Volume and Issue: unknown, P. 200389 - 200389

Published: March 1, 2025

Language: Английский

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Analysis of correlation between dietary fiber intake and risk of diabetic kidney disease in adults with type 2 diabetes mellitus: results from the United States National Health and Nutrition Examination Surveys 2009–2018

Renal Failure, Journal Year: 2025, Volume and Issue: 47(1)

Published: March 24, 2025

Objective Given the significant impact of diabetic kidney disease (DKD) on morbidity and mortality in patients with type 2 diabetes mellitus (T2DM) potential preventive role dietary factors, particularly fiber, this study aimed to investigate relationship between fiber intake risk DKD adults T2DM.

Language: Английский

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