Comment on “Cutaneous adverse reactions of COVID‐19 vaccines: A systematic review” DOI Creative Commons
Orla McFeely, Liana Victory, Emily Pender

et al.

Journal of Cosmetic Dermatology, Journal Year: 2023, Volume and Issue: 22(3), P. 732 - 733

Published: Jan. 27, 2023

We read with interest the article published by Shafie'ei et al.1 regarding a systematic review and meta-analysis of all reported cutaneous side effects COVID-19 vaccines. Our experience reactions is largely consistent prior reports mild, self-limiting reactions.2-4 note describing vasculitis following vaccination.5 In contrast to mild vaccination, we report case severe prolonged IgA single dose Janssen vaccine—Ad.26.COV2.S. A 60-year-old Caucasian woman self-presented emergency department due an extensive painful rash affecting her bilateral lower limbs. She described petechial limbs 8 h post vaccine 11 days prior. Within 10 days, she had developed palpable purpura circumferentially at both from knee distally as well thighs abdomen was referred dermatology physicians (Figure 1A). This on background psoriasis, psoriatic arthritis hypertension. Her longstanding medications included naproxen, amlodipine, fexofenadine, denied any symptoms infection. apyrexial, systems examination were unremarkable. Blood tests taken revealed mildly elevated c-reactive protein 14 mg/L (normal: <7 mg/L) erythrocyte sedimentation rate 26 mm within first hour <13 mm) normal white blood cell count 6.41 × 109/L 3.5–10.5 109/L). chest x-ray midstream urine showed no evidence At this time, super-potent topical steroids prescribed. punch biopsy right limb demonstrated findings leukocytoclastic 2). Direct immunofluorescence deposits vasculature. On follow-up review, tense bullae seen ankles. Treatment prescribed time consisted tapering oral steroids, antibiotics for secondary infection wound care. The ruptured leave multiple punched-out exquisitely ulcers 1B). It noted that urinary creatinine (UPCR) ratio uptrending rose value in excess 100 mg/mmol (normal 0–15 mg/mmol). Complete resolution aforementioned ulceration 5 months steroid treatment 1C). Imaging, colonoscopy, mammography negative malignancy. represents small vessel brought about activation neutrophils deposition perivascular sites.6 postvaccination resolving 4 weeks after onset.5 our case, complete corticosteroids, which longest case. Additionally, patient renal involvement preserved function. regular naproxen amlodipine commenced years presentation so deemed unlikely be causative. Malignancy out-ruled. While may have been coincidental, relationship between immune complex vaccination has reported5 most likely pathophysiological explanation patient's feel worth highlighting it demonstrates reaction vaccination. All authors contributed editing execution piece. None. conflict interest. provided written consent clinical images used publication.

Language: Английский

Sputnik‐V vaccine‐induced panniculitis as a local reactions DOI
Zahra Sahraei, Bahareh Abtahi‐Naeini, Ali Saffaei

et al.

Clinical Case Reports, Journal Year: 2022, Volume and Issue: 10(6)

Published: June 1, 2022

Here, a case of Sputnik-V vaccine-induced panniculitis was reported. The patient developed erythema, induration, and local tenderness at the injection site after 13 days injection. Ultra-sonography imaging showed inflammation in subcutaneous layers including fat tissue compatible with panniculitis. She received ibuprofen warm compress, all symptoms resolved.

Language: Английский

Citations

4
Pearls and pitfalls: Adverse cutaneous reactions after COVID-19 vaccination DOI

Mechelle A. Miller,

M. R. Tracey,

Meagan Simpson

et al.

Allergy and Asthma Proceedings, Journal Year: 2022, Volume and Issue: 43(6), P. 555 - 558

Published: Nov. 1, 2022

Background: Rashes after coronavirus disease of 2019 (COVID-19) mRNA vaccinations occur with typical and atypical presentations. Objective: The goal this article is to increase awareness review the various diagnosis management cutaneous adverse reactions associated COVID-19 for allergy/immunology fellows, residents, general physicians, practitioners. Methods: Pertinent information was included from patient's case. A available literature using works cited in most up-to-date reviews completed. Results: case a patient reaction vaccination as presented, followed by vaccinations. Conclusion: Providers should be aware different rashes Pearls pitfalls are provided.

Language: Английский

Citations

3
Effectiveness and safety of immune response to SARS‑CoV‑2 vaccine in patients with chronic kidney disease and dialysis: A systematic review and meta‑analysis DOI Open Access
Kejia Li, Xia Yang, Hua Ye

et al.

Biomedical Reports, Journal Year: 2024, Volume and Issue: 20(5)

Published: March 19, 2024

The coronavirus disease 2019 (COVID‑19) vaccination is the most effective way to prevent COVID‑19. However, for chronic kidney patients on long‑term dialysis, there a lack of evidence regarding efficacy and safety immune response vaccine. present meta‑analysis explores COVID‑19 vaccine in with (CKD) undergoing dialysis. PubMed, Web Science, Science Direct, Cochrane Library databases were systematically searched from January 1, 2020, December 31, 2022. Data analysis was performed using REVMAN 5.1s Stata14 software. Baseline data endpoint events extracted, mainly including age, sex, dialysis vintage, body mass index (BMI), type dose, history infection, seropositivity rate, antibody titer, pain at injection site, headache other events. included 33 trials involving 81,348 patients. CKD 80% (95 CI, 73‑87%). rate individuals without infection 76.48% (3,824/5,000), while 80.82% (1,858/2,299). standard mean difference titers or 27.73 (95% ‑19.58‑75.04). A total nine studies reported common adverse events: Pain accounting 18% 6‑29%), followed by fatigue headache, 8 4‑13%) 6% 2‑9%), respectively. benefitted ≥80%. Adverse such as fatigue, site may occur after but incidence low. 

Language: Английский

Citations

0
Exploring teledermatology in managing common inflammatory skin conditions: a systematic review DOI Creative Commons
Şule Gençoğlu

Journal of Health Sciences and Medicine, Journal Year: 2024, Volume and Issue: 7(3), P. 341 - 345

Published: May 27, 2024

This investigation delves into the advancing domain of telemedicine within dermatology, highlighting its potential to reshape forthcoming healthcare paradigms. Specifically focusing on utilization teledermatology for prevalent inflammatory skin conditions, this study synthesizes literature comprising meta-analyses, comprehensive reviews, editor correspondences, real-world investigations, case collections, and detailed reports. Adhering PRISMA (Preferred Reporting Items Systematic Reviews Meta-Analyses) standards, manuscript selection data extraction were meticulously executed. Initially, 121 relevant records identified through database surveys. Following screening, 110 articles met criteria in-depth evaluation, with 92 ultimately included in our review. Teledermatology, bolstered by exigencies pandemic, emerges as a viable alternative dermatological consultations foreseeable future. The rapid uptake refinement observed during crisis underscore further substantive advancements. Nonetheless, establishment structured guidelines governing implementation ongoing remains imperative.

Language: Английский

Citations

0
Comment on “Cutaneous adverse reactions of COVID‐19 vaccines: A systematic review” DOI Creative Commons
Orla McFeely, Liana Victory, Emily Pender

et al.

Journal of Cosmetic Dermatology, Journal Year: 2023, Volume and Issue: 22(3), P. 732 - 733

Published: Jan. 27, 2023

We read with interest the article published by Shafie'ei et al.1 regarding a systematic review and meta-analysis of all reported cutaneous side effects COVID-19 vaccines. Our experience reactions is largely consistent prior reports mild, self-limiting reactions.2-4 note describing vasculitis following vaccination.5 In contrast to mild vaccination, we report case severe prolonged IgA single dose Janssen vaccine—Ad.26.COV2.S. A 60-year-old Caucasian woman self-presented emergency department due an extensive painful rash affecting her bilateral lower limbs. She described petechial limbs 8 h post vaccine 11 days prior. Within 10 days, she had developed palpable purpura circumferentially at both from knee distally as well thighs abdomen was referred dermatology physicians (Figure 1A). This on background psoriasis, psoriatic arthritis hypertension. Her longstanding medications included naproxen, amlodipine, fexofenadine, denied any symptoms infection. apyrexial, systems examination were unremarkable. Blood tests taken revealed mildly elevated c-reactive protein 14 mg/L (normal: <7 mg/L) erythrocyte sedimentation rate 26 mm within first hour <13 mm) normal white blood cell count 6.41 × 109/L 3.5–10.5 109/L). chest x-ray midstream urine showed no evidence At this time, super-potent topical steroids prescribed. punch biopsy right limb demonstrated findings leukocytoclastic 2). Direct immunofluorescence deposits vasculature. On follow-up review, tense bullae seen ankles. Treatment prescribed time consisted tapering oral steroids, antibiotics for secondary infection wound care. The ruptured leave multiple punched-out exquisitely ulcers 1B). It noted that urinary creatinine (UPCR) ratio uptrending rose value in excess 100 mg/mmol (normal 0–15 mg/mmol). Complete resolution aforementioned ulceration 5 months steroid treatment 1C). Imaging, colonoscopy, mammography negative malignancy. represents small vessel brought about activation neutrophils deposition perivascular sites.6 postvaccination resolving 4 weeks after onset.5 our case, complete corticosteroids, which longest case. Additionally, patient renal involvement preserved function. regular naproxen amlodipine commenced years presentation so deemed unlikely be causative. Malignancy out-ruled. While may have been coincidental, relationship between immune complex vaccination has reported5 most likely pathophysiological explanation patient's feel worth highlighting it demonstrates reaction vaccination. All authors contributed editing execution piece. None. conflict interest. provided written consent clinical images used publication.

Language: Английский

Citations

1