Melatonin Interventions in Autism Spectrum Disorder: Sleep Regulation, Behavioral Outcomes, and Challenges Across the Lifespan DOI
Geir Bjørklund, Oleksandra Oleshchuk, Yana Ivankiv

et al.

Molecular Neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Language: Английский

Sleep and circadian disturbances in children with neurodevelopmental disorders DOI
Oliviero Bruni, Maria Breda,

Valeria Mammarella

et al.

Nature Reviews Neurology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 8, 2025

Language: Английский

Citations

1
Thinking Outside the Clock: Using the Whole Genome to Understand the Role of Circadian Rhythms in Human Health DOI Creative Commons
Danae Penichet

Journal of Biological Rhythms, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Language: Английский

Citations

0
Circadian Rhythmicity Consolidation is Positively Associated with Overall Developmental Status in Early Childhood DOI
Gonçalo Santos, Helena Schmidt,

Adrielle Holler Pykocz

et al.

Sleep and Vigilance, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 3, 2025

Language: Английский

Citations

0
Associations of ADHD symptom severity, sleep/circadian factors, depression and quality of life: Secondary analyses of the Netherlands Sleep Registry study DOI
Sunil Nair, Neha Deshpande, Catherine M. Hill

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

ABSTRACT Study objectives We investigated whether sleep disruption and circadian preference mediate the associations of ADHD symptom severity with depression quality life. Methods 1364 participants (mean: 51.86 [ SD = 0.37] years, 75% females) from a large-scale cross-sectional online survey (Netherlands Sleep Registry) completed sociodemographic questionnaire, Adult Rating Scale, Hospital Anxiety Depression Scale (HADS), Satisfaction With Life (SLS) Cantril Ladder (CL) (quality life measures), Insomnia Severity Index, Pittsburgh Quality Munich Chronotype Questionnaire. Results Higher was significantly associated ( p 0.03), lower < 0.001), insomnia later 0.01). No or factor mediated association symptoms (all > 0.1). Conversely, only (SLS: standardized beta -0.10, 95% CI [-0.12, -0.04]; CL: .103, [0.04, 0.16]). Conclusion life, primarily by severity. Future studies targeting complaints in this population may help mitigate their improve

Language: Английский

Citations

0
Associations Between Perinatal Dioxin Exposure and Circadian Clock Gene mRNA Expression in Children in Dioxin-Contaminated Areas of Vietnam DOI Creative Commons

Thao Ngoc Pham,

Hoa Thi Vu,

Takafumi Tasaki

et al.

Toxics, Journal Year: 2025, Volume and Issue: 13(3), P. 191 - 191

Published: March 7, 2025

We investigated the impact of perinatal dioxin exposure (indicated by levels in maternal breast milk) on clock gene mRNA expression buccal cells 9-year-old children from Da Nang birth cohort Vietnam using reverse transcription polymerase chain reaction. Of 56 boys and 34 girls (67% detection rate) whom PER1 was detected, BMAL1 detected only 16 15 girls. Dioxin were significantly higher with than without detection. In girls, relative associated greater 2,3,7,8-tetrachlorodibenzo-p-dioxin toxic equivalents polychlorinated dibenzodioxins dibenzofurans. Moreover, correlated shorter night sleep duration weekdays, holidays, hyperactivity scores. After adjusting for parity, dibenzofuran those Although verbal aggression hostility scores no such associations found boys. These findings suggest possible existence sex-specific effects circadian rhythms regulated genes, particularly BMAL1, leading to behavioral problems later life.

Language: Английский

Citations

0
Melatonin Interventions in Autism Spectrum Disorder: Sleep Regulation, Behavioral Outcomes, and Challenges Across the Lifespan DOI
Geir Bjørklund, Oleksandra Oleshchuk, Yana Ivankiv

et al.

Molecular Neurobiology, Journal Year: 2025, Volume and Issue: unknown

Published: March 26, 2025

Language: Английский

Citations

0