bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 14, 2024
Abstract
Despite
the
importance
of
identifying
predictable
regularities
for
knowledge
transfer
across
contexts,
generality
ecological
and
evolutionary
findings
is
yet
to
be
systematically
quantified.
We
present
first
large-scale
evaluation
using
new
metrics.
By
focusing
on
biologically
relevant
study
levels,
we
show
that
generalization
not
uncommon.
Overall,
20%
meta-analyses
will
produce
a
non-zero
effect
95%
time
in
future
replication
studies
with
70%
probability
observing
meaningful
effects
study-level
contexts.
argue
misconception
exceedingly
rare
due
conflating
within-study
between-study
variances
meta-analyses,
which
results
from
too
much
total
heterogeneity
(the
sum
variances).
encourage
our
proposed
approach
elucidate
general
patterns
underpinning
phenomena.
Despite
the
importance
of
identifying
predictable
regularities
for
knowledge
transfer
across
contexts,
generality
ecological
and
evolutionary
findings
is
yet
to
be
systematically
quantified.
We
present
first
large-scale
evaluation
using
new
metrics.
By
focusing
on
biologically
relevant
study
levels,
we
show
that
generalization
not
uncommon.
Overall,
20%
meta-analyses
will
produce
a
non-zero
effect
95%
time
in
future
replication
studies
with
70%
probability
observing
meaningful
effects
study-level
contexts.
argue
misconception
exceedingly
rare
due
conflating
within-study
between-study
variances
meta-analyses,
which
results
from
too
much
total
heterogeneity
(the
sum
variances).
encourage
our
proposed
approach
elucidate
general
patterns
underpinning
phenomena.
Despite
the
importance
of
identifying
predictable
regularities
for
knowledge
transfer
across
contexts,
generality
ecological
and
evolutionary
findings
is
yet
to
be
systematically
quantified.
We
present
first
large-scale
evaluation
using
new
metrics.
By
focusing
on
biologically
relevant
study
levels,
we
show
that
generalization
not
uncommon.
Overall,
20%
meta-analyses
will
produce
a
non-zero
effect
95%
time
in
future
replication
studies
with
70%
probability
observing
meaningful
effects
study-level
contexts.
argue
misconception
exceedingly
rare
due
conflating
within-study
between-study
variances
meta-analyses,
which
results
from
too
much
total
heterogeneity
(the
sum
variances).
encourage
our
proposed
approach
elucidate
general
patterns
underpinning
phenomena.
Conservation Physiology,
Journal Year:
2025,
Volume and Issue:
13(1)
Published: Jan. 1, 2025
Abstract
Natural
light–dark
cycles
are
responsible
for
synchronizing
an
animal’s
circadian
clock
with
environmental
conditions.
Consequently,
the
endocrine
system
is
vulnerable
to
changes
in
external
light
environment,
particularly
short-wavelength
blue
light.
Artificial
at
night
drastically
night-time
environment
by
masking
natural
and
disrupting
well-established
biological
rhythms.
The
introduction
of
blue-rich
lighting,
such
as
white
light-emitting
diodes
(LEDs),
may
increase
effects
on
wildlife.
However,
flexibility
spectral
composition
LED
lighting
presents
options
wildlife-sensitive
long-wavelength
amber
LEDs.
Here
we
examine
effect
spectra
physiology
a
nocturnal
marsupial.
Specifically,
investigate
(standard
urban
lighting)
LEDs
(proposed
hormones
cell-mediated
immunity
Krefft’s
glider
(Petaurus
notatus).
Melatonin
glucocorticoid
secretion
were
disrupted
following
exposure
both
Both
suppressed
melatonin,
whilst
was
under
increased
Despite
this
disturbance
did
not
detect
any
treatment
immune
response.
Our
findings
offer
novel
contribution
understanding
physiological
impacts
We
also
provide
evidence
that
can
disrupt
option
all
species.
Reproductive Medicine and Biology,
Journal Year:
2025,
Volume and Issue:
24(1)
Published: Jan. 1, 2025
Abstract
Background
The
biological
reproductive
process
requires
the
precise
coordination
of
annual
and
daily
signals
to
adapt
environmental
shifts.
Humans
animals
have
developed
shared
neuroendocrine
systems
that
adapted
seasonal
light
within
hypothalamic–pituitary
—gonadal
axis.
However,
stability
circadian
processes
is
at
risk
due
industrialization
contemporary
round‐the‐clock
lifestyles.
These
threats
include
skipping
breakfast,
excessive
artificial
illumination
during
inappropriate
hours
because
irregular
work
schedules,
nighttime
urban
lighting,
widespread
pollution
from
endocrine‐disrupting
chemicals.
This
review
aimed
explore
interplay
between
lifestyle
factors,
rhythms,
functions.
Methods
examined
reciprocal
influences
clocks
on
hormones,
exploring
underlying
mechanisms
their
implications
for
fertility
health.
We
emphasized
key
findings
regarding
molecular
clock
components,
endocrine
pathways,
critical
importance
synchronizing
rhythms
with
hormonal
cycles.
Main
Findings
intersection
endocrinology
biology
reveals
complex
interactions
regulation
rhythms.
Circadian
rhythm
misalignments
including
late‐night
negatively
impact
Conclusions
More
strategies
are
needed
mitigate
effects
disruption
Frontiers in Microbiology,
Journal Year:
2025,
Volume and Issue:
16
Published: March 25, 2025
Long
photoperiods
are
often
characterized
by
enhanced
oxidative
stress-induced
damage
to
skeletal
muscle,
reduced
melatonin
(MT)
levels
and
intestinal
microbiota
dysfunction
in
broilers.
In
this
study,
we
aimed
investigate
the
association
of
breast
muscle
morphology
with
cecal
broilers
under
different
photoperiods.
A
total
216
healthy
5-day-old
Arbor
Acres
(AA)
male
were
randomly
assigned
12
L:12D,
18
L:6D
24
L:0D
for
4
weeks
(L
=
hours
light,
D
darkness).
The
concentration
inflammatory
factors
MT
concentrations
was
measured
using
ELISA
kits,
whereas
examined
through
hematoxylin
(H)
eosin
(E)
staining,
composition
identified
16
s
rRNA
analysis.
Extended
light
exposure
significantly
improved
growth
rate
broilers,
but
decreased
feed
efficiency
(FE).
Furthermore,
it
upregulated
IL-1β,
IL-6
TNF-
α
induced
an
abnormal
morphology.
hypothalamus,
cecum
while
triggering
disorder.
Specifically,
there
significant
alteration
dominant
bacterial
phylum,
following
long
photoperiods,
abundance
Firmicutes
decreasing
Bacteroidota
increasing.
Notably,
relative
Lactobacillus
showed
a
positive
correlation
negative
cytokines.
conclusion,
present
findings
indicated
that
extended
levels,
which
related
disturbed
microbiota,
damaging
inducing
inflammation
Proceedings of the National Academy of Sciences,
Journal Year:
2024,
Volume and Issue:
121(44)
Published: Oct. 21, 2024
Climate
warming
enables
easier
access
and
operation
in
the
Arctic,
fostering
industrial
urban
development.
However,
there
is
no
comprehensive
pan-Arctic
overview
of
development,
which
crucial
for
planning
sustainable
development
region.
In
this
study,
we
utilize
satellite-derived
artificial
light
at
night
(ALAN)
data
to
quantify
hotspots
light-emitting
human
activity
across
Arctic
from
1992
2013.
We
find
that
out
16.4
million
km
2
analyzed
a
total
area
839,710
(5.14%)
lit
by
with
an
annual
increase
4.8%.
The
European
oil
gas
extraction
regions
Russia
Alaska
are
ALAN
up
third
land
lit,
while
Canadian
remains
dark
large
extent.
On
average,
only
15%
contains
settlement,
indicating
largely
attributable
activity.
With
provide
standardized
approach
spatially
assess
independent
economic
data.
Our
results
baseline
conservation
highly
vulnerable
