Published: April 18, 2025
Abstract The Gompertz equation describes exponential age-increases in animal mortality rate arising from biological aging. Its parameters, α and β , are widely used to evaluate lifespan-extending interventions human patterns: it is assumed that reduction corresponds deceleration of aging rate, reduced aging-independent mortality. However, this view has never been empirically validated. We therefore investigated the basis by simultaneous quantification age-related health long-lived populations nematode Caenorhabditis elegans . show arises not decelerated but expansion decrepitude longer-lived individuals, whereas This empirical re-evaluation Gompertzian inverts challenges long-standing ideas biodemography
Language: Английский